Faculty Member Lawrence C. Perlmuter

Lawrence C. Perlmuter, Ph.D. Professor and Research Professor Department of Medicine Phone: 847-578-8754 Email: lawrence.perlmuter@rosalindfranklin.edu
Research interests
1. Blood Pressure Regulation/ Cognition and Depression. When individuals shift posture from supine to standing, several changes are immediately required to maintain uninterrupted blood flow to the brain. Children and adults failing to show an adequate increase in blood pressure in response to standing also perform significantly more poorly on neuropsychological tests and display elevated depression. In African Americans and Caucasians we are examining the relationship between maternal anxiety and blood pressure regulation. Anxiety in the mother not only correlates with anxiety scores in their children, but also predicts blood pressure regulation in their children. 2. Perceived Control and Obesity and Children. We are examining the effectiveness of a multidisciplinary intervention to help reduce weight and body fat in children in the Hispanic and African American communities. We found that as BMI increases, effort in the classroom decreases. Thus, elevated BMI has more than just biological consequences. 3. Diabetes Research. We are examining how having a parent with diabetes affects coping with diabetes in adult children. Also, we are assessing the relationship between glycemic measures derived from continuous glucose monitoring and cognition and depression and finally we are examining how culture moderates the rate of cognitive decline in African Americans and Caucasians with diabetes mellitus.
Recent publications
Perlmuter, L.C., Sarda, G. Casavant,V., O,Hara, K. Hindes, M., Knott, P.T., Mosnaim, A.D. (in press). A review of orthostatic blood pressure regulation and its association with mood and cognition. Clinical Autonomic Research. Cheng, Yu-C, Vyas, A., Hymen, E., & Perlmuter, L.C. (2011). Gender Differences in Orthostatic Hypotension, The American Journal of the Medical Sciences, 343 (3), 221 – 225. Cassavant, V., Spivak, A. Marek, J., Chilamkurti, C., Perlmuter, L.C. (2010) Orthostatic Blood Pressure Regulation Correlates With Cognitive Function in Hispanic American Head Start Children. Vulnerable Child and Youth Studies, 5, 188-195. Ramaswamy, R. , Mirochna, M., & Perlmuter, L.C., (2010) The Negative Association of BMI with Classroom Effort in Elementary School Children. Journal of Child Health Care, 14, 161-169. Czajkowska, J., Ozhog, S., Smith E., & Perlmuter L.C. (2010). Cognition and hopelessness in individuals exhibiting subsyndromal orthostatic hypotension. Journal of Gerontology. Hindes, M., O¹Hara, K., Perlmuter, L.C. (2009). Subsyndromal Orthostatic Blood Pressure Regulation Correlates with Motor Skills in Head Start Children. International Journal of Psychophysiology, 74, 2, 101-105. Mosnaim, A.D., Abiola, R., Wolf, M., Perlmuter, L.C. (2009). Etiology and Risk Factors for Developing Orthostatic Hypotension. American Journal of Therapeutics. Perlmuter, L.C., Flanagan, B.P., Shah, P.H., & Singh, S. P (2009). Glycemic Control and Hypoglycemia. Response to Musen, Diabetes Care, 32, 1. (Comments and Responses). Perlmuter, L.C., Shah, P.H., Flanagan, B.P., Surampudi, V., Kosman, Y. (2009). Rate of Peripheral Glucose Change During Cognitive Testing Predicts Performance in Diabetes Mellitus. Journal of Diabetes, 1, 43-49. Sachman, J.L., Mayefsky, J.H, Ozhog, S. & Perlmuter, L.C. (2009). Birth Weight Predicts Subclinical Orthostatic Hypotension in Children. Human Ontogenetics, 3, 1-5. Perlmuter, L.C., Flanagan, B.P., Shah, P.H., & Singh, S. P. (2009). Glycemic Control and Hypoglycemia: Is the Loser the Winner? Diabetes Care, 31, 2072- 2076. (Invited Editorial)
Teaching
The Psychology of Learning History of Psychology Research Design and Program Evaluation