Aron D. Mosnaim, Ph.D. Professor Ph.D., 1969, Strathclyde (Scotland) Room:2.166 Phone:847-578-8675 Fax:847-578-3268 Email:aron.mosnaim@rosalindfrankin.edu

Ranade, V.V., Wolf, M.E. and Mosnaim, A.D.: Developments in antiarrhythmic drugs: An overview. Expert Opinion Investigational Drugs 4(11): 1-29, 1995

Puente, J., Diaz, M.A., Salas, M.A., Miranda, D., Gaggero, A., Wolf, M.E. and Mosnaim, A.D.: Studies of natural killer cell activity in a drug-free, healthy population. Response to a challenge with Taxol, Estramustine and Lipopolysaccharide. International J. Clinical Pharmacolology Therapy 33(8): 457-461, 1995

Mosnaim, A.D., Wolf, M.E., Curr, M., Mosnaim, J.m., Freitag, F. and Diamond, S.: Myths in migraine research: 1. Migraine and cluster headache patients are characterized by significant alterations in platelet monoamine oxidase activity. Headache Quarterly. Current Treatment and Research 7(3): 225-234, 1996

Mosnaim, A.D., Freitag, F., Ignacio, R., Salas, M.A., Karoum, F., Wolf, M.E. and Diamond, S.: Apparent lack of correlation between tyramine and phenylethylamine content and the occurrence of food-precipitated migraine. Reexamination of a variety of food products frequently consumed in the United States and commonly restricted in tyramine-free diets. Headache Quarterly. Current Treatment and Research 7(3): 239-249, 1996

Puente, J., Salas, M.A., Cañon, C., Miranda, D., Wolf, M.E. and Mosnaim, A.D.: Activation of protein tyrosine kinase: a possible requirement for fixed-bacteria and lipopolysaccharide-induced increase in human natural killer cell. J. Clinical Pharmacology Therapy 34(5): 212-218, 1996

Sepúlveda, C., Puente, J., Weinstein, C., Wolf, M.E. and Mosnaim, A. D.: Enhancement of natural killer cell activity in HIV-1 infected subjects by a mixture of the calcium ionophore A23187 and the phorbol ester TPA. Lack of response to a similar challenge with interleukin-2 or alpha-interferon. American J. Therapeutics 4(11-12): 413-421, 1997

Karoum, F., Wolf, M.E. and Mosnaim, A.D.: Effects of the administration of amphetamine, either alone or in combination with reserpine or cocaine, on regional brain beta-phenylethylamine and dopamine release. American J. Therapeutics 4(9-10): 333-342, 1997.

Mosnaim, A.D., Kulaga, H., Adams, J.A., Wolf, M.E., Freitag, F. and Diamond. S.: Flow cytometric analysis of lymphocyte subsets in migraine patients during and outside of an acute headache attack. Cephalalgia 18(4): 197-201, 1998.

Wolf, M.E., Moffat, M., Ranade, V., Somberg, J.C., Lehrer, E. and Mosnaim, A.D.: Lithium, hypercalcemia and arrythmia. J. Clin. Psychopharmacology (Peer reviewed Letter). 18: 420-423, 1998.

Miranda, D., Puente, J., Blanco, L., Wolf, M.E. and Mosnaim, A.D.: In vitro effect of bacterial lipopolysaccharide on the cytotoxicity of human natural killer cells. Research Communications Molecular Pathology and Pharmacology 100(1): 3-14, 1998.

Ranade, V., Molnar, J., Khokher, T., Agarwal, A., Mosnaim, A. D. and Somberg, J.: Effect of Angiotensin-converting enzyme therapy on QT interval dispersion. American J. Therapeutics 6: 257-261, 1999.

Wolf, M. E., Ranade, V., Molnar, J., Somberg, J. and Mosnaim, A. D.: Hypercalcemia, arrhythmia and mood stabilizers. J. Clin. Psychopharmacology, 20(2):260-264, 1999.

Valenzuela, M. A., Cartier, L., Collados, L., Kettlun, A. M., Araya, F., Concha, C., Flores, L., Wolf, M. E. and Mosnaim, A. D.: Gelatinase activity of matrix metalloproteinases in the cerebrospinal fluid of various patient populations. Res. Comm. Chemical Pathol. Pharmacol., 104(1):42-52, 1999.

Mosnaim, A. D., Wolf, M. E., Tao, D. N. Puente, J., Freitag, and Diamond, S.: Degradation kinetics of leucine-enkephalin by plasma samples from healthy controls and various patient populations. In vitro drug effects. American J. Therapeutics 7: 185-194, 2000.

Puente, J., Blanco, L., Montoya, M., Miranda, D., Contreras, I., Vinés, E., Wolf, M.E. and Mosnaim, A.D.: Effect of S. Typhi wild type and O-antigen mutants on human natural killer cell. Int. J. Immunopharmacol., 22:355-364, 2000.

Puente, J., Blanco, L., Carrasco, C., Miranda, M., Wolf, M.E. and Mosnaim, A.D.: Effect of Salmonella-infected human monocytes on natural killer cell cytotoxicity. In vitro studies. Int. Immunopharmacol., 1:1285-93, 2001.

Mosnaim, A. D., Puente, J., Saavedra, R., Diamond, S. and Wolf, M. E.: In vitro human plasma leucine(5)-enkephalin degradation is inhibited by a select number of drugs with the phenothiazine molecule in their chemical structure. Pharmacology; 67:6-13, 2003

Miranda, D., Blanco, L., Jara, P., Wolf, M. E., and Mosnaim, A.D.: Human natural killer cell lysis of Salmonella typhi intracellularly-infected U-937 cells. Res. Commun. Molec. Pathol. Pharmacol., 111:3-12, 2002

Miranda, D., Blanco, L., Jara, P., Wolf, M. E., and Mosnaim, A.D.: Lysis of Salmonella typhi intracellularly-infected U-937 cells by human natural killer cells. Effect of protein kinase inhibitors. Amer. J. Therapeutics, 10:32-39, 2003

Kettlun, A.M., Collados, C., García, L., Cartier, L.A., Wolf, M.E., Mosnaim, A.D. and Valenzuela, M.A.: Matrix metalloproteinases profile in patients with Creuztfeldt-Jakob Disease. Int. J. Clin. Pract., 57:475-8, 2003.

Mosnaim, A.D., Puente, J., Hoang, C., Ranade, V. and Wolf, M.E.: Inhibition of human plasma leucine-enkephalin aminopeptidase hydrolysis by various endogenous peptides and a select number of clinically used drugs. American J. Therapeutics 11: 459-466, 2004

Valenzuela, M.A., Cartier, L.A., Mosnaim, A.D., Wolf, M.E., Ketllun, A.M., Collados, C. and Garcia, L.: Proteinases and Prion Diseases, in Proteases in the Brain (U. Lendeckel and N. Hooper, eds), Springer Verlag, USA, pp. 179-201; 2005

Aron D. Mosnaim, Vasant V. Ranade, Marion E. Wolf, Javier Puente, and M. Antonieta Valenzuela.: Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents. American J. Therapeutics 13: 261-273, 2006

Puente J., Mosnaim, A.D. and Wolf, M.E.: Stress, Opioid Peptides and the Immune Response, in Cytokines, Stress and the Immune System (Plotnikoff, N.P., Murgo, A.J., Faith, R.E. and Good, R.A. eds.), CRC Press, Taylor & Francis Group, New York, pp.125-142, 2006

Mosnaim, A.D., Nguyen, T.D., Tse, R, Puente, J., Couceyro, P. and Wolf, M.E.: In vitro methionine-enkephalin degradation kinetics by human brain preparations. Neurochemical Research, 33:81-6, 2008

Mosnaim, A.D., Nguyen, T.D., Puente, J. and Wolf, M.E.: Degradation kinetics of methionine5-enkephalin by select brain areas from patients with chronic schizophrenia. American Journal of Therapeutics, 15:126-30, 2008

Puente, J., Jaque, M.P., Carrasco, C., Cruz, C., Valenzuela, M.A., Wolf, M.E. and Mosnaim A.D.: Triptan drugs, natural killer cell cytotoxicity and neutrophils pro-matrix metalloproteinase-9 secretion. Headache 48: 1482-9, 2008

Mosnaim AD, Saavedra R, Wolf ME. Bacitracin-sensitive aminopeptidase(s) degradation of Methionine(5)-enkephalin by human brain putamen and hippocampus preparations: inhibition by phenothiazine drugs. Am J Ther. 16:512-6, 2009.

Mosnaim AD, Abiola R, Wolf ME, Perlmuter LC. Etiology and risk factors for developing orthostatic hypotension. Am J Ther 17:86-91. Review. 2010

Mosnaim, A.D., Puente, J. and Wolf, M.E.: Biological correlates of migraine and cluster headaches: an overview of their potential use in diagnosis and treatment. Pragmatic and Observational Research. 1:25-32, 2010

Mosnaim AD, Chuang F, Wolf ME. Degradation Kinetics of Methionine5-Enkephalin by Cerebrospinal Fluid: In Vitro Studies. Am J Ther. 18:9-13, 2011

Perlmuter LC, Sarda G, Casavant V, O'Hara K, Hindes M, Knott PT, Mosnaim AD.  A review of orthostatic blood pressure regulation and its association with mood and cognition.  Clin Auton Res. 2011 Sep 25. [Epub ahead of print]