Mon. Aug . 13
Sequence analysis: databases and sequence retrieval
Lecture 1 (31 MB .mov)
Tue. Aug. 28
Sequence analysis: similarity and pairwise sequence alignment
Lecture 2 (22 MB .mov)
Wed. Sep. 12
Sequence analysis: multiple sequence alignment Phylogeny/molecular evolution/genetics
Lecture 3 (252 KB .mov)
Thu. Sep. 20
Primer design, specialized databases, and software collections
Lecture 4 (15 MB .mov)
Fri. Oct. 5
Protein secondary structure prediction RNA secondary structure prediction X-Ray crystallographic & NMR structures of proteins and nucleic acids
Lecture 5 (40 MB .mov)
Wed. Oct. 24
Computer-modeling of proteins, nucleic acids, drug molecules, etc.
If you put tomfoolery into a computer, nothing comes out but tomfoolery. But this tomfoolery, having passed through a very expensive machine, is somehow ennobled and no one dares criticize it. --Pierre Gallois
In so far as quantum mechanics is correct, chemical questions are problems in applied mathematics. --Eyring, Walter, & Kimball, 1944
The underlying physical laws necessary for the mathematical theory of a large part of physics and the whole of chemistry are thus completely known, and the difficulty is only that the exact application of these laws leads to equations much too complicated to be soluble. --P. A. M. Dirac
"I could have done it in a much more complicated way," said the Red Queen, immensely proud. --Lewis Carroll