Gloria E. Meredith Professor and Dean of the College of Pharmacy Ph.D., 1983 Georgetown University Room:HSB 2.622 Phone:847-578-8831 Fax:847-775-6586 Email: gloria.meredith@rosalindfranklin.edu

Rademacher DJ, Rosenkranz JA, Morshedi MM, Sullivan EM, Meredith GE. Amphetamine-associated contextual learning is accompanied by structural and functional plasticity in the basolateral amygdala. J Neurosci. (2010) 30:4676-86.

Zahm DS, Becker ML, Freiman AJ, Strauch S, Degarmo B, Geisler S, Meredith GE, Marinelli M. Fos after single and repeated self-administration of cocaine and saline in the rat: emphasis on the Basal forebrain and recalibration of expression. Neuropsychopharmacology. (2010) 35:445-63.

Meredith GE, Totterdell S, Beales M, Meshul CK. Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease. Exp Neurol. (2009) 219:334-40. Epub 2009 Jun 11.

Morshedi MM, Rademacher DJ, Meredith GE. Increased synapses in the medial prefrontal cortex are associated with repeated amphetamine administration. Synapse (2009) 63:126-35.

Meredith GE, Totterdell S, Potashkin JA, Surmeier DJ. Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol. Parkinsonism Relat Disord. (2008) 14 Suppl 2:S112-5. Epub 2008 Jun 27.

Meredith GE, Sonsalla PK, Chesselet MF. Animal models of Parkinson's disease progression. Acta Neuropathol. (2008) 115:385-398. Epub 2008 Feb 14.

Meredith GE, Baldo BA, Andrezjewski ME, Kelley AE. The structural basis for mapping behavior onto the ventral striatum and its subdivisions. Brain Struct Funct. (2008) 213:17-27. Epub 2008 Feb 7.

Morshedi MM, Meredith GE. Repeated amphetamine administration induces Fos in prefrontal cortical neurons that project to the lateral hypothalamus but not the nucleus accumbens or basolateral amygdala. Psychopharmacology (Berl). (2008) 197:179-189. Epub 2007 Dec 14.

Geisler S, Marinelli M, Degarmo B, Becker ML, Freiman AJ, Beales M, Meredith GE, Zahm DS. Prominent Activation of Brainstem and Pallidal Afferents of the Ventral Tegmental Area by Cocaine. Neuropsychopharmacology (2008) 33:2688-700. Epub 2007 Dec 19.

Rademacher DJ, Napier TC, Meredith GE. Context modulates the expression of conditioned motor sensitization, cellular activation and synaptophysin immunoreactivity. Eur J Neurosci. (2007) 26:2661-2668. Epub 2007 Oct 26.

Potashkin JA, Kang UJ, Loomis PA, Jodelka FM, Ding Y, Meredith GE. MPTP administration in mice changes the ratio of splice isoforms of fosB and rgs9. Brain Res. (2007) 1182:1-10. Epub 2007 Sep 14.

Morshedi MM, Meredith GE. Differential laminar effects of amphetamine on prefrontal parvalbumin interneurons. Neuroscience. (2007) 149:617-624. Epub 2007 Aug 14.

Chan CS, Guzman JN, Ilijic E, Mercer JN, Rick C, Tkatch T, Meredith GE, Surmeier DJ. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature. (2007) 447:1081-1086. Epub 2007 Jun 10.

Rademacher DJ, Kovacs B, Shen F, Napier TC, Meredith GE. The neural substrates of amphetamine conditioned place preference: implications for the formation of conditioned stimulus-reward associations. Eur J Neurosci. (2006) 24:2089-2097.

Shen F, Meredith GE, Napier TC. Amphetamine-induced place preference and conditioned motor sensitization requires activation of tyrosine kinase receptors in the hippocampus. J Neurosci. (2006) 26:11041-11051.

Meredith GE, Kang UJ. Behavioral models of Parkinson's disease in rodents: A new look at an old problem. Mov Disord. (2006) 21:1595-1606

Potashkin JA, Meredith GE. The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease. Antioxid Redox Signal. (2006) 8:144-151.

Saylor AJ, Meredith GE, Vercillo MS, Zahm DS, McGinty JF. BDNF heterozygous mice demonstrate age-related changes in striatal and nigral gene expression. Exp Neurol. (2006) 199:362-72.

Meredith GE, Steiner H. Amphetamine increases tyrosine kinase-B receptor expression in the dorsal striatum. Neuroreport. (2006) 17:75-78.

Totterdell S, Meredith GE. Localization of alpha-synuclein to identified fibers and synapses in the normal mouse brain. Neuroscience. (2005) 135:907-913.

Jin J, Meredith GE, Chen L, Zhou Y, Xu J, Shie FS, Lockhart P, Zhang J. Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson's disease. Brain Res Mol Brain Res. (2005) 134:119-138.

Dervan AG, Meshul CK, Beales M, McBean GJ, Moore C, Totterdell S, Snyder AK, Meredith GE. Astroglial plasticity and glutamate function in a chronic mouse model of Parkinson's disease. Exp Neurol. (2004) 190:145-156.

Meredith GE, Halliday GM, Totterdell S. A critical review of the development and importance of proteinaceous aggregates in animal models of Parkinson's disease: new insights into Lewy body formation. Parkinsonism Relat Disord. (2004) 10:191-202.

Totterdell S, Hanger D, Meredith GE. The ultrastructural distribution of alpha-synuclein-like protein in normal mouse brain. Brain Res. (2004) 1004:61-72.

Meredith GE, Switzer RC 3rd, Napier TC. Short-term, D2 receptor blockade induces synaptic degeneration, reduces levels of tyrosine hydroxylase and brain-derived neurotrophic factor, and enhances D2-mediated firing in the ventral pallidum. Brain Res. (2004) 995:14-22.

Lau YS, Petroske E, Meredith GE, Wang JQ. Elevated neuronal nitric oxide synthase expression in chronic haloperidol-treated rats. Neuropharmacology. (2003) 45:986-94.

De Souza IE, Dawson NM, Clifford JJ, Waddington JL, Meredith GE. Relationship of orofacial movements to behavioural repertoire as assessed topographically over the course of 6-month haloperidol treatment followed by 4-month withdrawal. Psychopharmacology (Berl). (2003) 16:28-34.

Lau YS, Meredith GE. From drugs of abuse to parkinsonism. The MPTP mouse model of Parkinson's disease. Methods Mol Med. (2003) 79:103-16.

Totterdell, S. and G.E. Meredith. 2003. Immunocytochemical characterisation of catecholaminergic neurons in the rat striatum following dopamine depleting lesions. In: Basal Ganglia V. (Eds. Graybiel A., et al.) Plenum Press, New York.

Totterdell S., Lau Y.-S., Petroske E., Callen S., Meredith G.E. 2002. Progressive neurodegeneration in a new mouse model of Parkinson’s disease. Implications for neuropathology. In: Basal Ganglia VI. (Eds. R. Faull, et al.) Plenum Press, New York.

Meredith GE, Totterdell S, Petroske E, Santa Cruz K, Callison RC, Lau YS. Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease. Brain Res. (2002) 956:156-65.

Meredith GE, Callen S, Scheuer DA. Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration. Brain Res. (2002) 949:218-27.

Petroske E, Meredith GE, Callen S, Totterdell S, Lau YS. Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment. Neuroscience. (2001) 106:589-601.

Bothwell S, Meredith GE, Phillips J, Staunton H, Doherty C, Grigorenko E, Glazier S, Deadwyler SA, O'Donovan CA, Farrell M. Neuronal hypertrophy in the neocortex of patients with temporal lobe epilepsy. J Neurosci. (2001) 21:4789-800.

Dawson NM, Hamid EH, Egan MF, Meredith GE. Changes in the pattern of brain-derived neurotrophic factor immunoreactivity in the rat brain after acute and subchronic haloperidol treatment. Synapse. (2001) 39:70-81.