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Donghee.kim@rosalindfranklin.edu

Teaching:

• Cardiovascular Physiology
• Autonomic Nervous System
• Cardiac Electrophysiology / Electrocardiogram

Current Research Areas:

• Two-Pore Domain K⁺ channels (K_2P channels): 

• Transient Receptor Potential (TRP) Ion Channels:  

Recent Publications

• Kang DW, Han JH, Talley EM, Bayliss DA, Kim D.  Functional expression of TASK-1/TASK-3 heteromer in cerebellar granule neurons . J. Physiol. Jan;554(1):64-77, 2004. 

• Kang, DW, Mariash E, Kim D.  Functional expression of TRESK-2, a new member of the two-pore domain K+ channel. J. Biol. Chem. 279:28063-28070, 2004..

• Kang DW, Choe CY, Kim D.  Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK.  J. Physiol. 564.1, 103-116, 2005

• Kim, D.  Physiology and pharmacology of two-pore domain K+ channels.  Current Pharmaceutical Design 11: 2717-2736, 2005 (review).

• Kang DW, Kim D.  TREK-1 and TRESK are two major background K+ channels in dorsal root ganglion neurons.  Am J Physiol 2006 Jul;291(1):C138-46. .

• Kang DW. Han JH, Kim D.  Mechanism of inhibition of TREK-2 by acetylcholine via Gq.  Am J Physiol 2006 Oct;291(4):C649-56.

• Kang, DW, Choe C, Cavanaugh EJ, Kim D.  Properties of Single TREK-2 (K2P10.1) Channels Expressed in Mammalian cells. J. Physiol. 583.1: 57-69, 2007.

• Kim D, Cavanaugh EJ.  Requirement of a cytosolic factor for activation of TRPA1: role of inorganic polyphosphates.  J. Neurosci. 27:6500-6509, 2007.

• Cavanaugh EJ, Simkin D, Kim D.  Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol, and Ca reveals different functional channel states.  Neuroscience 154:1467-1476, 2008

• Kim D, Cavanaugh EJ, Simkin D.  Inhibition of transient receptor potential A1 by phosphatidylinositol-4,5-bisphosphate.  Am. J. Physiol. Cell Physiol. 295:C920C99, 2008.

• Cruz-Orengo L, Dhaka A, Heuermann RJ, Yong TJ, Montana MC, Cavanaugh EJ, Kim D, Story GM.  Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1.  Molecular Pain 4:30 (1-9), 2008

• Simkin D, Cavanaugh EJ, Kim D.  Control of single channel conductance of K2P10.1 (TREK-2) by the amino terminus: role of alternative translation initiation.  J. Physiol. (coming soon)