Jun-yong Choe, Ph.D.

Assistant Professor
Chicago Medical School
Biochemistry and Molecular Biology
Room: 3.166
Building: BSB
Phone: 847.578.8627
Fax: 847.578.3240
Junyong.Choe@rosalindfranklin.edu
Publications

Smirnova, I., Kasho, V., Sugihara, J., Choe, J., and Kaback, H.R., (2009) "Residues in the H+ translocation site define the pKa for sugar binding to LacY." Biochemistry, 48, 8852-8860. [medline]

Moiseeva, N., Bau, R., Swensson, S.D., Markland, F.S., Choe, J., Liu, Z.J., Allaire. M., (2008) "Crystal structure of Acostatin, a dimeric disintegrin from Southern copperhead (Agkistrodon contortrix contortrix) at 1.7 Å resolution." Acta Cryst. D 64, 466-70. [medline]

Smirnova, I., Kasho, V., Choe, J., Altenbach, C., Hubbell, W.L., and Kaback, H.R., (2007) “Sugar binding induces an outward facing conformation of LacY." Proc. Natl. Acad. Sci. USA. 104, 16504-9. [medline]

Lee, J., Kang, H., Moon, Y., Cho, D., Kim, D., Choe, J.Y., Honzatko, R.B., and Robyt, J.F., (2006) “Cloning, Expression, and Characterization of an Extracellular Enolase from Leuconostoc mesenteroides." FEMS Microbiol. Lett. 259, 240-8. [medline]

Choe, J.,  Dimov, S., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005 “Structure of Human Nucleoside-Diphosphate Kinase 3 (Protein Data Bank Identification Code: 1ZS6)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Artz, J.D., Gao, M., Lew, J., Zhao, Y., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Hui, R., (2005) “Structure of Nuclear transport factor 2 (Ntf2) from Cryptosporidium Parvumuman (Protein Data Bank Identification Code: 1ZO2)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human Muscle Pyruvate Kinase (Protein Data Bank Identification Code: 1ZJH)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human Adenylate Kinase 3 Like 1 (Protein Data Bank Identification Code: 1ZD8)", Structural Genomics Consortium. [sgc entry

Mulichak, A.M., Lew, J., Artz, J., Choe, J., Walker, J.R., Zhao, Y., Sundstrom, M.,  Arrowsmith, C.,  Edwards, A., Bochkarev, A.,  Hui, R., Gao, M., (2005) “Crystal Structure of Guanylate Kinase from Plasmodium Falciparum (Protein Data Bank Identification Code: 1Z6G)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human ADP-Ribosylation Factor-Like 10B (Protein Data Bank Identification Code: 1ZD9)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human ADP-Ribosylation Factor-Like 5 (Protein Data Bank Identification Code: 1Z6Y)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human ADP-Ribosylation Factor 4 (Protein Data Bank Identification Code: 1Z6X)",Structural Genomics Consortium. [sgc entry]

Walker, J.R., Choe, J.,  Avvakumov, G.V.,  Newman, E.M.,  Mackenzie, F.,   Sundstrom, M.,  Arrowsmith, C.,  Edwards, A., Bochkarev, A.,  Dhe-Paganon, S., (2005) “Structure of Novel Ubiquitin-Conjugating Enzyme (Protein Data Bank Identification Code: 1YRV)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Atanassova, A., Arrowsmith, C.,  Edwards, A., Sundstrom, M.,   Bochkarev, A.,  Park, H., (2005) “Structure of Human ADP-Ribosylation Factor-Like 8 (Protein Data Bank Identification Code: 1YZG)", Structural Genomics Consortium. [sgc entry]

Choe, J.,  Avvakumov, G.V.,  Newman, E.M.,  Mackenzie, F.,  Kozieradzki, I.,  Bochkarev, A.,  Sundstrom, M.,  Arrowsmith, C.,  Edwards, A.,  Dhe-Paganon, S., (2005) “Structure of Ubiquitin-Conjugating Enzyme E2-25KDa (Huntington Interacting Protein 2; Protein Data Bank Identification Code: 1YLA)", Structural Genomics Consortium. [sgc entry]

Choe, J.Y., Iancu, C.V., Fromm, H.J., and Honzatko, R.B. (2003) "Metaphosphate in the Active Site of Fructose-1,6-bisphosphatase." J. Biol. Chem. 278, 16015-20.

Choe, J.Y., Nelson, S.W., Fromm, H.J., and Honzatko, R.B. (2003) "Interaction of Tl+ with Product Complexes of Fructose-1,6-bisphosphatase." J. Biol. Chem. 278, 16008-14.

Choe, J.Y., Nelson, S.W.,Arienti, K.L., Axe,F.U., Collins,T.L., Jones,T.K.,Kimmich,R.D.,Michael ,J., Newman, M.L., Norvell, K., Ripka, W.C., Romano, S.J., Short,K.M., Slee,D.H., Fromm,H.J., and Honzatko,R.B. (2003) "Inhibition of Fructose-1,6-bisphosphatase by a New Class of Allosteric Effectors." J. Biol. Chem. 278, 51176-83.

Park, M., Ryu, J., Kim, D., Choe, J., and Robyt, J.F. (2001) "Characterization of Leuconostoc mesenteroides B-742CB Dextransucrase Expressed in Escherichia coli." J. Microbiol. Biotechnol. 11, 628-635.

Iancu, C.V., Borza, T., Choe, J.Y., Fromm, H.J., and Honzatko,R.B. (2001) "Recombinant mouse muscle adenylosuccinate synthetase: overexpression, kinetics, and crystal structure." J. Biol. Chem. 276, 42146-52.

Nelson, S.W., Iancu, C.V., Choe, J.Y., Honzatko, R.B., and Fromm, H.J. (2000)"Tryptophan fluorescence reveals the conformational state of a dynamic loop in recombinant porcine fructose-1,6-bisphosphatase." Biochemistry 39, 8565-73.

Nelson, S.W., Choe, J.Y., Honzatko,R.B., and Fromm, H.J. (2000) "Mutations in the hinge of a dynamic loop broadly influence functional properties of fructose-1,6 bisphosphatase." J. Biol Chem. 275, 29986-92.

Choe, J.Y., Fromm, H.J., and Honzatko, R.B. (2000) "Crystal structures of fructose-1,6-bisphosphatase: mechanism of catalysis and allosteric inhibition revealed in product complexes." Biochemistry 39, 8565-74.

Choe, J.Y., Poland, B.W., Fromm, H.J., and Honzatko, R.B.(1999) "Mechanistic implications from crystalline complexes of wild-type and mutant adenylosuccinate synthetases from Escherichia coli." Biochemistry 38, 6953-61.

Choe, J.Y., Poland, B.W., Fromm, H.J., and Honzatko, R.B. (1998) "Role of conformationaly dynamic loop in cation activation and allosteric regulation of recombinant porcine fructose-1,6-bisphosphatase." Biochemistry 37, 11441-50.

Ferutz, K., Choe, J.Y., Honzatko, R.B., and Fromm, H.J. (1998) "Directed mutations in the poorly defined region of porcine liver fructose 1,6 bisphosphatase significantly affects catalysis and the mechanism of AMP inhibition." J. Biol Chem. 273, 17511-6.

Robyt, J.F., Choe, J., Hahn, R.S., Fox, J.D. and Fuchs, E.B. (1996) "Acid modification of starch granules in alcohols: reactions in mixtures of two alcohols combined in different ratios." Carbohydrate Research 283, 141-50.

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