Heinz Steiner, Ph.D.

Professor & Chair
Ph.D., 1989, University of Duesseldorf (Germany)

Office: 2.120
Building: BSB
Phone: 847-578-8679
Fax: 847-578-3268
E-mail: Heinz.Steiner@rosalindfranklin.edu

Publications

Steiner, H., Warren, B.L., Van Waes, V. and Bolaños-Guzmán, C.A., Life-long consequences of juvenile exposure to psychotropic drugs on brain and behavior. Prog. Brain Res. 211:13-30, 2014.

Unterwald, E.M., Page, M.E., Brown, T.B., Miller, J.S., Ruiz, M., Pescatore, K.A., Xu, B., Reichardt, L.F., Beverley, J., Tang, B., Steiner, H., Thomas, E.A. and Ehrlich, M.E., Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons. Mol. Neurodegener. 8:47, 2013.

Steiner, H., LRRKing up the right trees? On figuring out the effects of mutant LRRK2 and other Parkinson's disease-related genes. Basal Ganglia 3:73-76, 2013.

Van Waes, V., Vandrevala, M., Beverley, J. and Steiner, H., Selective serotonin re-uptake inhibitors potentiate gene blunting induced by repeated methylphenidate treatment: Zif268 versus Homer1a. Addict. Biol. Epub 13 Jun 2013.

Steiner, H. and Van Waes, V., Addiction-related gene regulation: risks of exposure to cognitive enhancers vs. other psychostimulants. Prog. Neurobiol. 100:60-80, 2013.

Van Waes, V., Carr, B., Beverley, J.A. and Steiner, H., Fluoxetine potentiation of methylphenidate-induced neuropeptide expression in the striatum occurs selectively in direct pathway (striatonigral) neurons.  J. Neurochem. 122:1054-1064, 2012.

Van Waes, V., Beverley, J. A., Siman,  H., Tseng,  K. Y. and Steiner, H., CB1 cannabinoid receptor expression in the striatum: association with corticostriatal circuits and developmental regulation.  Front. Pharmacol. 3:21, 2012.

Steiner, H., Basal Ganglia - A Willisian journal. Basal Ganglia 1:175-176, 2011 (editorial).

Van Waes, V., Tseng, K. Y. and Steiner, H., GPR88 - a putative signaling molecule predominantly expressed in the striatum: Cellular localization and developmental regulation. >Basal Ganglia 1:83-89, 2011.

Heng, L., Beverley, J. A., Steiner, H. and Tseng, K. Y., Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas. Synapse  65:278-286, 2011.

Ondracek, J. M., Willuhn, I., Steiner, H. and West, A. R., Interactions between procedural learning and cocaine exposure alter spontaneous and cortically evoked spike activity in the dorsal striatum. Front. Neurosci. 4:206, 2010.

Van Waes, V., Beverley, J., Marinelli, M. and Steiner, H., Selective serotonin reuptake inhibitor antidepressants potentiate methylphenidate (Ritalin)-induced gene regulation in the adolescent striatum. Eur. J. Neurosci. 32:435-447, 2010.

Steiner, H. and Tseng, K. Y. (Eds.), Handbook of Basal Ganglia Structure and Function; Handbook of Behavioral Neuroscience Series, Vol. 20; Elsevier, London, 2010.

Steiner, H., Psychostimulant-induced gene regulation in corticostriatal circuits. In: Handbook of Basal Ganglia Structure and Function, H. Steiner and K. Y. Tseng (Eds.), Handbook of Behavioral Neuroscience Series, Vol. 20; Elsevier, London, pp. 501-525, 2010.

Steiner, H.
, Van Waes, V. and Marinelli, M., Fluoxetine potentiates methylphenidate-induced gene regulation in addiction-related brain regions: Concerns for use of cognitive enhancers? Biol. Psychiatry 67:592-594, 2010.

Willuhn, I. and Steiner, H., Motor-skill learning in a novel running-wheel paradigm: Long-term memory consolidation by D1 receptors in the striatum. In: The Basal Ganglia IX, H. J. Groenewegen et al. (Eds.), Springer, Berlin, pp. 255-267, 2009.

Unal, C. T., Beverley, J. A., Willuhn, I. and Steiner, H., Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a. Eur. J. Neurosci. 29:1615-1626, 2009.

Willuhn, I. and Steiner, H., Skill-memory consolidation in the striatum: Critical for late but not early long-term memory and stabilized by cocaine. Behav. Brain Res. 199:103-107, 2009.

Willuhn, I. and Steiner, H., Motor-skill learning in a novel running-wheel task is dependent on D1 dopamine receptors in the striatum. Neuroscience 153:249-258, 2008.

Tropea, T. F., Guerriero, R. M., Willuhn, I., Unterwald, E. M., Ehrlich, M. E., Steiner, H. and Kosofsky, B. E., Augmented D1 dopamine receptor signaling and immediate-early gene induction in adult striatum following prenatal cocaine. Biol. Psychiatry 63:1066-1074, 2008.

Yano, M. and Steiner, H., Methylphenidate and cocaine: the same effects on gene regulation? Trends Pharmacol. Sci. 28:588-596, 2007.

Steiner, H.
, Basal ganglia – cortex interactions: Regulation of cortical function by D1 dopamine receptors in the striatum. In: Monoaminergic Modulation of Cortical Excitability, K. Y. Tseng and M. Atzori (Eds.), Springer, Berlin, pp. 265-285, 2007.

Cotterly, L., Beverley, J. A., Yano, M. and Steiner, H., Dysregulation of gene induction in corticostriatal circuits after repeated methylphenidate treatment in adolescent rats: Differential effects on zif 268 and homer 1a. Eur. J. Neurosci. 25:3617-3628, 2007.

Yano, M., Beverley, J. A. and Steiner, H., Inhibition of methylphenidate-induced gene expression in the striatum by local blockade of D1 dopamine receptors: interhemispheric effects. Neuroscience 140:699-709, 2006.

Willuhn, I. and Steiner, H., Motor-skill learning-associated gene regulation in the striatum: Effects of cocaine. Neuropsychopharmacology 31:2669-2682, 2006.

Meredith, G. E. and Steiner, H., Amphetamine increases tyrosine kinase-B receptor expression in the dorsal striatum. Neuroreport 17:75-78, 2006.

Willuhn, I. and Steiner, H., Motor learning-related gene regulation in the striatum: Effects of cocaine. In: The Basal Ganglia VIII, J. P. Bolam et al. (Eds.), Springer, Berlin, pp. 197-207, 2005.

Yano, M. and Steiner, H., Methylphenidate (Ritalin) induces expression of Homer 1a and zif 268 in specific corticostriatal circuits. Neuroscience 132:855-865, 2005.

Yano, M. and Steiner, H., Topography of methylphenidate (Ritalin)-induced gene regulation in the striatum: Differential effects on c-fos, substance P and opioid peptides. Neuropsychopharmacology 30:901-915, 2005.

Brandon, C. L. and Steiner, H., Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum. Eur. J. Neurosci. 18:1584-1592, 2003.

Willuhn, I., Sun, W. and Steiner, H., Topography of cocaine-induced gene regulation in the rat striatum: Relationship to cortical inputs and role of behavioural context. Eur. J. Neurosci. 17:1053-1066, 2003.

Steiner, H.
and Kitai, S. T., Unilateral striatal dopamine depletion: time-dependent effects on cortical function and behavioural correlates. Eur. J. Neurosci. 14:1390-1404, 2001.

Carta, A. R., Gerfen, C. R. and Steiner, H., Cocaine effects on gene regulation in the striatum and behavior: Increased sensitivity in D3 dopamine receptor-deficient mice. Neuroreport 11:2395-2399, 2000.

Steiner, H.
and Kitai, S. T., Regulation of rat cortex function by D1 dopamine receptors in the striatum. J. Neurosci. 20:5449-5460, 2000.

Steiner, H.
, Blum, M., Kitai, S. T. and Fedi, P., Differential expression of ErbB3 and ErbB4 neuregulin receptors in dopamine neurons and forebrain areas of the adult rat. Exp. Neurol. 159:494-503, 1999.

Steiner, H.
and Gerfen, C. R., Enkephalin regulates acute D2 dopamine receptor antagonist-induced immediate-early gene expression in striatal neurons. Neuroscience 88:795-810, 1999.

Steiner, H., Bonner, T. I., Zimmer, A. M., Kitai, S. T. and Zimmer, A., Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice. Proc. Natl. Acad. Sci. USA 96:5786-5790, 1999.

Steiner, H.
and Gerfen, C. R., Role of dynorphin and enkephalin in the regulation of striatal output pathways and behavior. Exp. Brain Res. 123:60-76, 1998.

Gerfen, C. R., Keefe, K. A. and Steiner, H., Dopamine-mediated gene regulation in the striatum. Adv. Pharmacol. 42:670-673, 1998.

Steiner, H., Fuchs, S. and Accili, D., D3 dopamine receptor-deficient mouse: evidence for reduced anxiety. Physiol. Behav. 63:137-141, 1998.

Melzer, P. and Steiner, H., Stimulus-dependent expression of immediate-early genes in rat somatosensory cortex. J. Comp. Neurol. 380:145-153, 1997.

Steiner, H.
and Gerfen, C. R., Dynorphin regulates D1 dopamine receptor-mediated responses in the striatum: relative contributions of pre- and postsynaptic mechanisms in dorsal and ventral striatum demonstrated by altered immediate-early gene induction. J. Comp. Neurol. 376:530-541, 1996.

Konig, M., Zimmer, A. M., Steiner, H., Holmes, P. V., Crawley, J. N., Brownstein, M. J. and Zimmer, A., Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin. Nature 383:535-538, 1996.

Drago, J., Gerfen, C. R., Westphal, H. and Steiner, H., D1 dopamine receptor-deficient mouse: cocaine-induced regulation of immediate-early gene and substance P expression in the striatum. Neuroscience 74:813-823, 1996.

Accili, D., Fishburn, C. S., Drago, J., Steiner, H., Lachowicz, J. E., Park, B. H., Gauda, E. B., Lee, E. J., Cool, M. H., Sibley, D. R., Gerfen, C. R., Westphal, H. and Fuchs S., A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc. Natl. Acad. Sci. USA 93:1945-1949, 1996.

Life in Discovery
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