Cancer Research
Cancer research at RFUMS involves the use of an array of multidisciplinary approaches to study the:

  • Molecular biology of Kaposi’s sarcoma associated herpes virus  (KSHV) implicated in the etiology of AIDS-related Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease, in order to elucidate the mechanism of pathogenesis (Bala Chandran)
  • Epstein-Barr virus (EBV) transforming protein and its role in manipulating cellular signaling pathways involved in tumor formation (Note: EBV is associated with Burkitt’s lymphoma, nasopharyngeal carcinoma, as well as certain types of Hodgkin disease and gastric cancers) (David Everly)
  • Arachidonic acid pathway in KSHV pathogenesis (Neelam Sharma-Walia)
  • Nuclear and mitochondrial cross talk by signal molecules in controlling aerobicglycolysis that is essential for the growth of lymphoma and other cancer cells (Chao-Lan Yu)
  • Glutamate and glutamate receptors that are specifically over expressed in human EBV+ and KSHV+ B-cell lymphoma cells with a goal of utilizing animal models to determine the chemo-therapeutic potential of FDA-approved anti-glutamate and glu-receptor drugs to control and/or eliminate EBV+ and KSHV+ tumor cells (Mohanan Veettil)
  • Hepatitis C viral infection induced inflammation and liver oncogenesis (Gulam Waris).
  • Compartmentalization of the nucleus as it contributes to genome function and regulates genome organization in cancer (Mirek Dundr).
Life in Discovery
Internal Funding Opportunities
3333 Green Bay Road, North Chicago, Il 60064-3095 • 847-578-3000