X-ray Facility

BMB Macromolecular X-ray Core Facility

David H. T. Harrison, Ph.D.
BMB secondary appointment
Assistant Director

Henry Symersky, Ph.D.
Facility Manager

PHONE: 847-578-8474



X-ray Facility

The facility is located at L141 of the main campus, 3333 Green Bay Road, North Chicago, IL 60064. It supports structural biology projects that utilize X-ray crystallography and molecular modeling. Core instrumentation for crystallization consists of the robot Mosquito from TPP Labtech, and the Korima UV fluorescence visualization system. In-house diffraction experiments are performed on an R-axis area detector or a Bruker CCD detector, using the high-brilliance Rigaku generator, a rotating copper anode, and Oxford mirrors. Cryogenic cooling is provided by the Rigaku X-stream or the Oxford Cryosystem. Synchrotron diffraction data is collected at APS Argonne National Laboratory near Chicago. Rosalind Franklin University is a member of SER-CAT (www.ser.aps.anl.gov) with regular access to APS beamlines 22ID and 22BM. Computing is based on a 6TB Linux server and several NFS-connected client computers with 3D graphics.  Multiple software suites are kept up to date by Structural Biology Grid (www.sbgrid.org). Modeling packages include Molecular Operating Environment (www.chemcomp.com) and SCHRODINGER (www.schrodinger.com).










Life in Discovery
3333 Green Bay Road, North Chicago, Il 60064-3095 • 847-578-3000