School of Graduate and Postdoctoral Studies
Molecular and Cellular Sciences Archive
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2014-2015 Series Dates

November 12, 2014
What Drives Cancers Caused by Human Papillomaviruses?
Paul F. Lambert, PhD − University of Wisconsin, Madison

December 10, 2014

January 14, 2015
Role of the Inflammasome and Related Cytokines During Bacterial Infections
Fabio Re, PhD − Department of Microbiology and Immunology, RFUMS

February 11, 2015
Crystal Structure of a Glucose Transporter and Its Mechanism
Jun-yong Choe, PhD − Department of Biochemistry and Molecular Biology, RFUMS

March 11, 2015
Corticostriatal Control of Decision Making
Andrew Holmes, PhD − Laboratory of Behavioral and Genomic Neuroscience, NIH

April 08, 2015
The Role of Ubiquitination in Cell Surface Stability of CFTR: Therapeutic Implications for Cystic Fibrosis
James Collawan, PhD - University of Alabama at Birmingham

*May 12, 2015 at 3:00
Systems Neuromedicine: Implications for Alzheimer's and Parkinson's Disease
Howard Federoff, MD, PhD − Georgetown University, Washington DC
*Note change of date and time

2013-2014 Series Dates

Wednesday September 11, 2013 (East Pod)
Raymond N. DuBois, Jr., M.D., Ph.D., Executive Director of The Biodesign Institute Arizona State University - Inflammatory Mediators, Cytokine Networks and Cancer Progression

Wednesday October 9, 2013 (East Pod)
Elizabeth M. Wilson, Ph.D., Professor of Pediatrics and Biochemistry and Biophysics at University of North Carolina at Chapel Hill - Proto-Oncogene Activity of the Primate-Specific Androgen Receptor Coregulator MAGE-A11

Wednesday November 06, 2013 (East Pod)*
Martin Friedlander, M.D., Ph.D**, Professor of Cell and Molecular Biology at Scripps College,California Campus - Stemming Vision Loss with Stem Cells: Ras, VEGF and HIFs Modulation during Retinal Angiogenesis
*Please note the date change.** 7th Werner Straus Memorial Seminar

Wednesday December 11, 2013 - Canceled

Wednesday January 8, 2014 (Centennial Room)
Heinz Steiner, Ph.D. Professor and Chair, Department of Cellular and Molecular Pharmacology at Rosalind Franklin University of Medicine and Science- Addiction-Related Gene Regulation: Why You Don’t Want to Mix Ritalin with Prozac

Wednesday February 12, 2014 (Centennial Room)
Carl White, Ph.D. Assistant Professor of Physiology and Biophysics at Rosalind Franklin University of Medicine and Science- Calcium and Hydrogen Sulfide Signaling in the Pathophysiology of Obesity

Wednesday March 12, 2014 (Centennial Room)
Ole Isacson, MD - Professor of Neurology (Neuroscience) Harvard Medical School, Director of Neuroregeneration Laboratories and Center for Neuroregeneration Research at McLean Hospital/Harvard Medical School - Discovering the Neurobiology of Parkinson's Disease to Provide Innovative Therapies

Wednesday April 9, 2014 (Centennial Room)
Phoebe Ray, PhD - Professor of Biochemistry & Molecular Biology, The University of Chicago - The Machinery of Site-Specific Recombination & Transposition

Wednesday May 07, 2014 (Centennial Room)
Gordon MG Shepherd, MD, PhD - Assistant Professor, Department of Physiology, Northwestern University, Feinberg School of Medicine - Cortical circuits in the mouse's motor system


Wednesday, October 10, 2012
Karen Colley, PhD, Professor of Biochemistry and Molecular Genetics, Dean of the Graduate School, University of Illinois, Chicago School of Medicine - “Polysialic Acid: Biosynthesis of an Anti-Adhesive Glycan with Roles in Brain Development and Cancer Metastasis"

Wednesday, November 14, 2012
Kathryn Jones, PhD, Professor and Chair, Department of Anatomy & Cell Biology, Indiana University School of Medicine - “CD4+T Cell-Mediated Neuroprotection: Relevance to Motoneuron Injury and Disease"

Wednesday, December 12, 2012
Eric Beyer, MD, PhD, Professor of Pediatrics, Cell Physiology, Cancer Biology and Molecular Medicine, University of Chicago - Title: Pathways of Gap Junction Degradation and Implications for Disease

Wednesday, January 09, 2013
Marina E. Wolf, PhD, Professor and Chair, Department of Neuroscience, Rosalind Franklin University of Medicine and Science - “AMPA Receptor Plasticity: A Target for Treating Cocaine Addiction"

6th Werner Straus Seminar
Wednesday, February 20, 2013
Mirek Dundr, PhD , Assistant Professor, Department of Cell Biology and Anatomy, Rosalind Franklin University of Medicine and Science "Dynamic Organization of Gene Expression"

Wednesday, March 13, 2013
J. David Sweatt, PhD, , Evelyn F. McKnight Chair, Dept of Neurobiology, Director, McKnight Brain Institute, University of Alabama at Birmingham - “Epigenetic Mechanisms in Memory Formation"

Wednesday, April 10, 2013
Ted Dawson, MD/PhD, Leonard and Madlyn Abramson Professor of Neurodegenerative Diseases, Department of Neuroscience, Institute for Cell Engineering, Johns Hopkins University - Baltimore, MD - “Molecular Insights into Parkinson’s Disease Pathogenesis”


Wednesday, September 14, 2011
George L. Kenyon, Ph. D., Professor in the College of Pharmacy, University of Michigan - "Part I: Creatine Kinase: Structure & Function of an Energetic Enzyme Energetic Enzyme; Part II: Finding a Home at the NSF for Your Chemical Biology Proposal"

Wednesday, November 09, 2011
Bernard Roizman, Sc.D., Professor, Departments of Microbiology and Molecular Genetics & Cell Biology, The University of Chicago - "The Strategy of Conquest: Herpes Simplex vs the Host"

Wednesday, December 14, 2011
Julie Kauer, Ph.D., Professor, Molecular Pharmacology, Physiology and Biotechnology, Brown University - "Drugs, stress and plasticity of VTA synapses"

Wednesday, January 11, 2012
Adrian Gross, MD, Associate Professor, Department of Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science - "Structural Basis of Potassium Channel Function"

Wednesday, February 08, 2012
Neelam Sharma-Walia , Ph.D., Assistant Professor, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science - "Kaposi’s Sarcoma-Associated Human Herpes Virus (KSHV) Induced Eicosanoids: Lipid Mediators of Inflammation"

Wednesday, March 14, 2012
Douglas C. Rees, Ph.D., Roscoe Gilkey Dickinson Professor of Chemistry, California Institute of Technology/Howard Hughes Medical Institute - ABC Transporters: Structures and Mechanisms

Friday, March 30, 2012
George A. Calin, M.D., Ph.D., Associate Professor, Department of Experimental Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX - "Coding and non-coding mix in cancers - the lessons for scientists and use for patients"

Wednesday, May 09, 2012
David E. Nichols, Ph.D., Robert C. and Charlotte P. Anderson Distinguished Chair in Pharmacology - Purdue University Department of Medicinal Chemistry and Molecular Pharmacology - Title: Multidisciplinary Approaches to the study of G Protein Coupled Receptors


Wednesday, October 13, 2010
Karl Herrup, Ph.D., Professor and Chair, Cell Biology & Neuroscience, Rutgers, "A Fresh Look at the Death of Nerve Cells in Human Disease: New Pathways, New Targets"

Wednesday, November 10, 2010
William Skach, MD, Professor of Biochemistry & Molecular Biology, Oregon Health & Science University, "A Fluorescence-Based Approach to Cotranslational Protein Folding"

Wednesday, January 12, 2011
Neil Bradbury, Ph.D., Associate Professor, Physiology & Biophysics, Rosalind Franklin University of Medicine and Science, "Playing in Traffic: Novel Mechanisms of Ion Channel Targeting"

Wednesday, February 9, 2011
Judith Potashkin, Ph.D., Associate Professor, Cellular & Molecular Pharmacology, Rosalind Franklin University of Medicine and Science

Wednesday, March 9, 2011
D. James Surmeier, Ph.D., Professor & Chair, Department of Physiology, Feinberg School of Medicine, Northwestern University, "Dopaminergic Control of Striatal Excitability and Synaptic Plasticity"

Wednesday, April 13, 2011
Billy G. Hudson, Ph.D., Eliot V. Newman Professor of Medicine and Pathology Director, Vanderbilt Center for Matrix Biology, Vanderbilt University "Ramifications of Collagen IV Structure to Human Disease"

5th Annual Werner Straus Seminar
Wednesday, May 11, 2011
Robert H. Singer, Albert Einstein College of Medicine, "Following Single mRNAs from Birth to Death in Living Cells"


4th Annual Werner Straus Seminar
Wednesday, September 9, 2009
Dr. Michael Terns, Ph.D., Professor of Biochemistry and Molecular Biology & Genetics, University of Georgia, "Trafficking of Human Telomerase to Telomeres"

Wednesday, October 14, 2009
Dr. Zissimos Mourelatos, Associate Professor and Director of Neuropathology, University of Pennsylvania School of Medicine, "Piwi proteins and piRNAs"

Wednesday, November 11, 2009
Dr. Gregory Petsko, D. Phil., Professor of Biochemistry and Chemistry, Brandeis University "The Structural Enzymology of Parkinson's Disease"

Wednesday, December 2, 2009
Dr. Mitchell Drumm, Professor of Pediatric Pulmonology, Case Western Reserve "Of Mice and Men: A Chapter on Cystic Fibrosis"

Tuesday, January 26, 2010
Dr. John Walker, Director, MRC Mitochondrial Biology Unit, Cambridge, UK "Mitochondrion in Health and Disease"

Wednesday, February 10, 2010
Dr. Daniel Peterson , Associate Professor of Neuroscience, Director Center for Stem Cell and Regenerative Medicine, RFUMS, "Stem Cell Recruitment as a Therapeutic Strategy for Tissue Repair"

Wednesday, March 10, 2010
Dr. Joseph DiMario, Professor, Department of Cell Biology and Anatomy, RFUMS, "Skeletal Muscle Fiber Type Formation: Cell Intrinsic vs. Extrinsic Regulation"

Wednesday, April 14, 2010
Dr. Benjamin J. Blencowe, Ph.D., Professor, University of Toronto , "Alternative Splicing Regulatory Networks"


Wednesday, September 10, 2008 Dr. Gordon Hager, National Cancer Institute, NIH, "Interaction of Nuclear Receptors with the Chromatin Landscape"

Wednesday, October 22, 2008
Dr. Clemens Scherzer, Co-Director, Harvard NeuroDiscovery Biomarker Program "Parkinson's Disease and the Transcriptional Regulation of Alpha Synuclein"

Wednesday, December 3, 2008
Dr. Michael D. Ehlers, Professor and Wakeman Scholar, Howard Hughes Medical Institute, Department of Neurobiology, Duke: "Memory and Membrane Dynamics in Dendritic Microdomains"

Wednesday, January 14, 2009
Dr. Carl C. Correll, Associate Professor, Biochemistry and Molecular Biology, Rosalind Franklin University of Medicine and Science, " RNA Chaperone Activity in Ribosome Biogenesis"

Wednesday, February 11, 2009
Dr. Bala Chandran, Professor and Chair, Department of Microbiology and Immunology, Rosalind Franklin University of Medicine and Science, "Kaposi's Sarcoma Associated Herpesvirus Interactions with Integrins - Gateway for Host Signaling for Successful Infection"

Wednesday, April 8, 2009
Dr. Yuri Lazebnik, Cold Spring Harbor Laboratory, GIN, CIN and Cell Promiscuity: Can Viruses Contribute to Cancer by Fusing Cells?

Wednesday, May 13, 2009

Third Annual Werner Straus Memorial Seminar
Dr. Benjamin Glick, Professor, Department of Molecular Genetics and Cell Biology, University of Chicago "Where Do Little Golgi Stacks Come From?"


Wednesday, September 12, 2007
Second Werner Straus Memorial Seminar
Dr. Tom Misteli, Senior Investigator, Cell Biology of Genomes Group, National Cancer Institute, NIH
The surprising link between nuclear architecture and human aging

Wednesday, October 10, 2007
Dr. John Schiller, Senior Investigator, National Cancer Institute, NIH
Papillomavirus L2: Multifunctional Virion Protein and 2nd Generation
Vaccine Target

Wednesday, December 12, 2007
Dr. Philip Thomas, Professor of Physiology, University of Texas Southwestern Medical School, Dallas
Protein misfolding as a basis of human disease

Wednesday, January 9, 2008
Dr. Kevin Foskett, Professor of Physiology, University of Pennsylvania School of Medicine
Calcium signaling in apoptosis and Alzheimer's disease: Two sides of the same coin?

Wednesday, March 12, 2008
Dr. Joseph Gall, Staff Member, Department of Embryology, Carnegie Institution of Washington
The cell biology of snRNP biogenesis Wednesday, April 9, 2008
Dr. Mary Jeanne Kreek, Professor, Rockefeller University, NY
Opioids and the Addictions

Wednesday, May 14, 2008
Dr. Glen Andrews, Professor, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center




Wednesday, October 11, 2006
First Werner Straus Memorial Seminar
Dr. Bernhard Dobberstein, Professor of Molecular Biology, ZMBH, Univ. of Heidelberg
Signal sequences: More than just greasy peptides

Wednesday, November 8, 2006
Dr. Roberta Brinton, Professor of Pharmacology and Pharmaceutical Sciences, Univ. of Southern California
Estrogen action in brain: Translating basic science discovery into therapeutic reality for the brain

Wednesday, December 13, 2006
Dr. Petra Arck, Professor, Charité, Campus Virchow Klinikum, Berlin
Endocrine-Immune Circuitry Challenging Pregnancy Maintenance and Fetal Health

Wednesday, January 10, 2007
Dr. Robert J. Wenthold, Senior Investigator, NIDCD/NIH
Trafficking of NMDA Receptors

Wednesday, February 28, 2007
Dr. Greg Matera, Professor of Genetics, Case Western Reserve University
Drosophila Models of Spinal Muscular Atrophy and Ribonucleoprotein (RNP) Biogenesis

Wednesday, May 9, 2007
Dr. Tom Steitz, Sterling Professor of Molecular Biophysics and Biochemistry, Yale University
Macromolecular Machines




Wednesday, October 12, 2005
Dr. Margaret Fahnestock, Dept. of Psychiatry & Behavioral Neurosciences, McMaster University
ProNGF and ProBDNF in Neuroprotection and Neurodegeneration

Monday, November 7, 2005
Dr. Hideaki Nagase, Imperial College London, United Kingdom
Metalloproteinases and Osteoarthritis: Understanding the role of non-catalytic domains in cartilage matrix degradation

Monday, November 21, 2005
Werner Straus Memorial Symposium
The Cell Biology of Renal Epithelium and Tubules, 1:00 - 3:30 p.m.

Wednesday, December 14, 2005
Dr. Robert Campenot, Dept of Cell Biology, University of Alberta
Retrograde signaling by NGF without retrograde transport and other insights from work with compartmented cultures of sympathetic neurons

Wednesday, January 11, 2006
Dr. David Kaplan, Dept. of Molec. & Medical Genetics, University of Toronto
Signal transduction by neurotrophins in neurons and neural tumor cells

Wednesday, February 8, 2006
Dr. Brian Wilkinson, Dept. of Microbiology, Illinois State University
The Staphylococcus aureus cell wall stress stimulon: implications in antimicrobial action, resistance, and drug discovery

Wednesday, March 8, 2006
Dr. Linda Pike, Dept. of Biochemistry & Molecular Biophysics, Washington University
Lipid rafts and the regulation of EGF receptor function

Wednesday, April 5, 2006
Dr. John F. Marshall, Dept. of Neurobiology & Behavior, UC-Irvine
Neural circuits and molecular mechanisms underlying cocaine memories

Wednesday, May 10, 2006
Dr. Michael Levine, Dept. of Psychiatry, UCLA
Mouse models of Huntington's and Parkinson's diseases: What have we learned from electrophysiology?

Wednesday. May 17, 2006
Dr. Ann M. Graybiel, Dept. of Brain and Cognitive Sciences, Massachusetts Institute of Technology
The basal ganglia and cognitive pattern generators




Wednesday, September 29, 2004
Dr. Mary Hendrix, President & Scientific Director, Children's Memorial Institute for Educat & Research
Professor, Dept of Pediatrics, Northwestern University School of Medicine
Plasticity of Aggressive Tumor Cells: Role of the Microenvironment

Wednesday, November 17, 2004
Dr. Virginia Sanders, Professor, Molecular Virology, Immunology, & Medical Genetics, Ohio State University
It Takes Nerve to Tell a B Cell what to Do

Wednesday, December 8, 2004
Dr. Richard Silverman, John Evans Professor of Chemistry, Northwestern University
Mechanism and Inhibition of Nitric Oxide Synthase. Potential Treatment for Neurodegeneration

Wednesday, January 19, 2005
Dr. J. Paul Bolam, MRC Anatomic Neuropharmacology Unit, Oxford University, England
The Functional Organization of the Basal Ganglia

Wednesday, February 9, 2005
Dr. John Guzowski, Assistant Professor, Dept. of Neurosciences, University of New Mexico
FISHing for Memories: Genes, Cell Networks, & Behavior

Wednesday, March 9, 2005
Dr. Deborah Nelson, Neurobiology, Pharmacology & Physiology, University of Chicago
Modulation of Hippocampal Synaptic Function by the Chloride Channel ClC-3

Wednesday, April 13, 2005
Dr. Anthony Grace, Professor, Dept of Neuroscience, University of Pittsburgh
Interactions between Prefrontal Cortex and Amygdala: Relevance to the Pathophysiology of Schizophrenia




Wednesday, September 10, 2003
Dr. Eric Nestler, University of Texas Southwestern Medical Center
Molecular Mechanisms of Drug Addiction

Wednesday, October 1, 2003
Dr. Martin Friedlander, Scripps Research Institute & Clinic
Stemming Vision Loss with Stem Cells: Adult Bone Marrow Derived Stem Cells have Vasculo- and Neurotrophic Effects in the Eye

Wednesday, November 12, 2003
Dr. Anne B. Croy, University of Guelph
Contributions of Lymphocytes to Preparation for Pregnancy

Wednesday, January 14, 2004
Dr. Jack Kessler, Northwestern University

Wednesday, February 11, 2004
Dr. Michael Sarras, FUHS/CMS
The Role of Cell-Extracellular Matrix Interactions during Developmental and Regenerative Processes: Analysis of Hydra and Zebrafish as Model Systems.

Wednesday, March 10, 2004
Dr. Evelyn Ralston, National Institutes of Health
Plasticity of Skeletal Muscle Fibers: Organelles and Cytoskeleton

Wednesday, April 14, 2004
Dr. Daniel Goodenough, Harvard Medical School
Diverse Functions of Gap Junctions Revealed by Targeted Deletion of Connexin Genes

Wednesday, May 12, 2004
Dr. Gopal Thinakaran, University of Chicago
Gamma-Secretase Processing of Alzheimer's Disease Amyloid Precursor in Lipid Rafts




Wednesday, September 18, 2002
Dr. Jonathan Leis, Northwestern University
Mechanism of Retrovirus Proteolytic Processing and Assembly

Wednesday, October 9, 2002
Dr. Robert Vassar, Northwestern University
BACE-1: A prime Therapeutic Target for Alzheimer's Disease

Wednesday, November 13, 2002
Dr. Carolyn Machamer, Johns Hopkins University
Caspase-2 and the Golgi Complex in Apoptosis

Wednesday, December 11, 2002
Dr. Véronique Lefebvre, Lerner Research Institute, Cleveland Clinic
Critical Determinants of Cell Fate and Differentiation: Sry-Related HMG Box (Sox) Transcription Factors

Wednesday, January 8, 2003
Dr. Michael Rudnicki, University of Ottawa
Myogenic Specification of Adult Stem Cells in Muscle.

Wednesday, February 12, 2003.
Dr. Elizabeth Sztul, The University of Alabama at Birmingham
Molecular Cross-talk between Secretion and Degradation

Wednesday, March 12, 2003
Dr. Ian Duncan, University of Wisconsin
Stem cell biology and brain repair: is transplantation feasible in human myelin disorders?

Wednesday, April 9, 2003
Dr. Paul Witkovsky, NYU School of Medicine
Dopamine and Retinal Function

Wednesday, May 14, 2003
Dr. Lakshmi Devi, Mount Sinai School of Medicine, NY.
Modulation of Function by G-Protein Coupled Receptor Dimerization/Oligomerization.



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