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Podcast Archive

HelixTalk #141 - What You Need to Know about Hepatorenal Syndrome: New Definitions, Treatments, and Clinical Pearls

Date posted: December 28, 2021, 6:00 am

In this episode, we provide a concise overview of the diagnosis and treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI) with a focus on the new HRS-1 definition (now called HRS-AKI), new data with terlipressin, and the AASLD 2021 guidelines.

HelixTalk #140 - The Ultimate Guide to SSRIs: An In-Depth Drug Class Review

Date posted: December 7, 2021, 6:00 am

In this episode, we review the pharmacology, indications, adverse effects, and unique drug characteristics of the most common SSRIs on the market.

HelixTalk Episode #139 - They Did What?! FDA Approval of Aducanumab for Alzheimer’s Disease

Date posted: November 16, 2021, 6:00 am

In this episode, we discuss the recent accelerated approval of the new monoclonal antibody-based treatment agent, aducanumab (Aduhelm), by the FDA. We dive into the drug approval process, the efficacy and safety data, and the behind-the-scenes story of the FDA approval. Furthermore, we will present the controversy behind the approval and what it means for stakeholders.

HelixTalk Episode #138 - Hidden Pharmaceutics: The Fascinating Science Behind Dosage Formulations

Date posted: October 26, 2021, 6:00 am

In this episode, we discuss the fascinating science of pharmaceutics with Dr. Kristen Ahlschwede and Dr. Rahul Deshmukh. We explore how dosage forms and excipients play an important role in how a drug product behaves in the human body with a particular focus on fentanyl patches, osmotic tablets (with laser-drilled holes), Depakote Sprinkles, and IV amiodarone.

HelixTalk Episode #137 - It’s Time for PBM Reform: How PBMs Have Hurt Pharmacies and Increased Drug Costs

Date posted: October 5, 2021, 6:00 am

In this episode, we reveal what goes on behind the scenes for drug pricing and pharmacy reimbursement with Dr. Benjamin Jolley. Our discussion covers important concepts like PBMs, DIR fees, MAC pricing, and even possible upcoming changes at the federal government.

HelixTalk Episode #136 - Major Recommendations from the 2021 CHEST Anticoagulation for VTE Disease Guideline Updates

Date posted: September 14, 2021, 6:00 am

In this episode, we discuss the recently published major updates in the 9th edition of the anticoagulation guidelines from CHEST. These new recommendations range from initiation of therapy, secondary prevention, and management of post-thrombotic syndrome.

HelixTalk Episode #135 - Top Four Medications Myths: BUSTED!

Date posted: August 24, 2021, 6:00 am

In this episode, we debunk four medication myths that have persisted for decades: metronidazole and alcohol; statins and hepatotoxicity; cidal vs. static antibiotics; and "sulfa" allergies.

HelixTalk Episode #134 - Hypertensive Emergencies Demystified: A Brief Clinical Review

Date posted: August 3, 2021, 6:00 am

In this episode, we provide a concise review of the diagnostic criteria and general treatment approach to patients with hypertensive emergencies.

HelixTalk Episode #133 - Tell Me More: Exploring Covid 19 Vaccine Hesitancy and Solutions!

Date posted: July 13, 2021, 6:00 am

In this episode, we will explore depths of COVID 19 vaccine hesitancy - what it is, how to identify and address it, and some helpful resources.

HelixTalk Episode #132 - The Warp Speed of Covid-19 Vaccine Authorizations: Timeline and Discussion with Dr. Archana Chatterjee

Date posted: June 22, 2021, 6:00 am

In this episode, we will explore the history of COVID vaccine development and have a heart-to-heart conversation with Dr. Archana Chatterjee regarding her role as a dean of the RFUMS Chicago Medical School, her career path, and her position and functions on the FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC).