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Ann K. Snyder, PhD

Associate Professor & Vice Chair, Department of Cellular and Molecular Pharmacology
Department of Cellular and Molecular Pharmacology

Ann Snyder graduated from Pennsylvania State University.  She earned an M.S. in 1968 and a PhD in 1971 from the University of Illinois, Urbana-Champaign, both in Physiology. Following postdoctoral work at Duke University Medical School, in Durham, North Carolina and Rush Medical School in Chicago, Illinois she joined the Endocrine and Metabolic Research Program of the Veterans Affairs Medical Center in North Chicago, Illinois as a Research Physiologist. She joined the faculty of the Department of Medicine of the Chicago Medical School in 1989 as a Research Assistant Professor and the Department of Cellular and Molecular Pharmacology as a Research Associate Professor in 1996 and was promoted to Associate Professor in 2007.  She has been an Adjunct Associate Professor in the Department of Basic Biomedical Sciences of the Scholl College of Podiatric Medicine since 2007.

Research

Glial and neuronal glucose transport and metabolism; Neurotoxic effects of alcohol; Fetal Alcohol Syndrome; Fuel-mediated teratogenesis

Interactions between alcohol and carbohydrate metabolism may have profound effects in the developing and the mature individual. Our past research utilizing a rat model of the fetal alcohol syndrome has shown effects on placental glucose transfer and on circulating and tissue glucose levels and the hormonal environment. We have also demonstrated effects of alcohol on glucose uptake and utilization using invitro systems, including brain cell cultures from fetal and neonatal rats and whole rat embryos cultured during organogenesis. The goal of our current studies is to characterize changes are induced by alcohol in the expression of glucose transporter genes during organogenesis, in brain cell cultures and in the neonatal rat brain and to relate these effects to alterations of glucose n utilization and cell functionality and viability.

 Effect of ethanol on growth and development of cultured rat embryos

SELECTED Publications 

Book Chapters

  • Snyder AK, Singh SP, Ehmann S: Effects of ethanol on substrate uptake and incorporation in primary astrocyte cultures. In: Lancaster F, ed Alcohol and Glial Cells.  Research Monograph No. 27, National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, 1994
  • Snyder AK: Responses of glia to alcohol.  In The Role of Glia in Neurotoxicity, Aschner M, Kimelberg H, eds, CRC Press, 1996

Links