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Scot Kristian Hill, PhD

Associate Professor

Dr. Scot Kristian Hill, Associate Professor in the Department of Psychology in the College of Health Professions received his Ph.D. in School Psychology from Ball State University, specializing in Clinical Neuropsychology. Dr. Hill completed Postdoctoral Fellowships in clinical neuropsychology at Thomas Jefferson University Hospital and the Brain Behavior Laboratory at the University of Pennsylvania School of Medicine. Prior to joining RFUMS, Dr. Hill was a member of the Center for Cognitive Medicine at the University of Illinois at Chicago.

Dr. Hill’s early research focused on learning disabilities and the impact of neurodevelopmental issues on cognitive abilities. More recently, his interests lie in neurocognitive deficits associated with psychosis; the neural and cognitive bases of working memory dysfunction in schizophrenia, particularly frontostriatal communications; electrophysiological and neuropsychological markers of psychosis; intermediate phenotypes shared among psychotic disorders; and neurotransmitter regulation in psychosis (genetic and systems level). Research methods include behavioral analysis, neuropsychological testing, electroencephalography (EEG), genotype analyses, functional magnetic resonance imaging (fMRI), multivariate analyses (pattern classification, subtype identification, structural equations modeling). Research reports have appeared in several areas including Neuropsychology, Psychiatry, Neuroscience, and Psychology journals.

Honors include NIMH National Research Service Award Fellowship, NIMH Mentored Patient-Oriented Research Career Development Award, and NIH Clinical Research Loan Repayment Program Award. Dr. Hill has been the principal investigator on several extramural and foundation grants and has served as co-investigator or consultant on several projects investigating disease and treatment related effects on neuroscognition in first episode and chronic schizophrenia, shared genetic liability underlying schizophrenia and bipolar disorder, and cognitive and affective dysfunction in pediatric bipolar disorder.

Are You a Prospective Graduate Student? Dr. Hill will be accepting a student for the 2020/2021 academic year.

Research

Dr. Hill is currently involved in researching neurocognition in psychosis. Specifically, Dr. Hill has ongoing involvement in the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP) research group. In addition, Dr. Hill has ongoing research with his lab at Rosalind Franklin University researching working memory deficits in schizophrenia across neuropsychological, genetic, and electroencephalographic methods. The lab's most recent publication involved integration of genetic and neuropsychological assessment data in understanding serial order processing deficits across varied conditions of stimulus recall in individual's with schizophrenia.

Research Lab

Research Topics

  1. Neurocognition in psychosis
  2. Cognitive treatment effects
  3. Intermediate cognitive phenotypes

Dr. Hill is currently involved in researching neurocognition in psychosis. Specifically, Dr. Hill has ongoing involvement in the Bipolar and Schizophrenia Network on Intermediate Phenotypes (B-SNIP) research group. In addition, Dr. Hill has ongoing research with his lab at Rosalind Franklin University researching working memory deficits in schizophrenia across neuropsychological, genetic, and electroencephalographic methods. The lab's most recent publication involved integration of genetic and neuropsychological assessment data in understanding serial order processing deficits across varied conditions of stimulus recall in individual's with schizophrenia.

Graduate Students

  Emily Kalscheur, M.S.
  Zachary Resch, M.S.
  Maura Wolfe, M.S.
  Alec Neale, M.S.
Tasha Rhoads, M.S.
Tasha is a fourth year student in the PhD program. Her current research interests include identifying neurophysiological and neuropsychological biomarkers of psychotic disorders as well as psychological and cognitive predictors of surgical outcome and success. This year, Tasha is completing a clinical practicum at the University of Chicago in the adult neuropsychological assessment clinic. In her free time, she enjoys attending concerts, sewing, cooking, traveling, and gardening.
Milena Gotra, M.S.
Milena is a third year student in the Ph.D. program. Her research interests are in using neuroimaging and computerized paradigms to evaluate cognition, with recent projects in identifying divergent neuropathological and longitudinal cognitive profiles of psychosis. This year, Milena is completing a clinical practicum at the University of Chicago Medical Center where she completes neuropsychological evaluations of patients with a wide range of conditions, including epilepsy, degenerative disorders, TBI, tumors, and developmental disorders. In her free time, she enjoys going for walks with her dog and traveling back to Russia.
Lindsey Holbrook
Lindsey is a third year student in the PhD program on the neuropsychology track. Her research interests include traumatic brain injury, PTSD, emotional injury, and rehabilitation. This year, she is completing a clinical practicum at NorthShore University Health Systems where she is administering neuropsychological examinations to patients screening for dementia, learning disorders, ADHD, and pre-surgical evaluations, along with report writing. In her free time, Lindsey likes to cook, sing, play piano, workout, spend time with friends, watch movies.
Cari Cohen, M.S.
Cari is a 2nd year student in the PhD program. Her research interests include aging, Alzheimer's disease, and mild cognitive impairment. This year, Cari is completing a clinical practicum at NorthShore University HealthSystem where she administers neuropsychological assessments for adults. In her free time, Cari enjoys reading, exercising, playing tennis, traveling, and spending time with her family and friends.
Erin Kaseda
Erin is a second year student in the PhD program, completing the neuropsychology and health psychology tracks. Her research interests include the effects of cancer and epilepsy on cognition, and cognitive biomarkers of medical illness. This year, she is completing two therapy practicums at the Lovell VA where she works with veterans with comorbid medical and neurodegenerative conditions and at the Healthy Families clinic where she works with uninsured children and families in the Waukegan area. Erin is also the cognitive science representative on the APA Science Student Council for 2019-2021.

Alumni

Hayley Amsbaugh, PhD
Jenna Axelrod, PhD
Alison Buchholz, PhD 
Tarra Carrathers, PhD
William Hochberger, PhD
Courtney Nelson, PhD
Jarret Roseberry, PhD

Publications

Hochberger WC, Combs T, Reilly JL, Keefe RSE, Keshavan MS, Pearlson GD, Tamminga CA, Clementz BA, Sweeney JA, Hill SK. (2018). Decline from expected cognitive ability is modestly familial across psychotic disorders. Schizophrenia Research, 192, 300-307.

Nelson, C., Hill, S.K. (2018) et al. “Beneficial and Adverse Effects of Antipsychotic Medication on Cognitive Flexibility Are Related to COMT Genotype in First Episode Psychosis.” Schizophrenia Research.

Hochberger, W. C., Hill S.K., et al (2018). “P3 Amplitude Attenuation Secondary to Increases in Target-to-Target Interval (TTI) during Spatial Serial Order Recall: Implications for EEG Models of Working Memory Function.” International Journal of Neuroscience, pp. 1–22.

Shafee, R., Hill S.K., et al (2018). “Polygenic Risk for Schizophrenia and Measured Domains of Cognition in Individuals with Psychosis and Controls.” Translational Psychiatry, vol. 8, no. 1.

Combs, T. Hill S.K., et al. (2018) “Deficient Single Item Maintenance Following Intact Updating in Schizophrenia.” Schizophrenia Research, vol. 195, pp. 353–356.

Hochberger, W.C., Hill S.K., et al. (2018) “Deviation from Expected Cognitive Ability across Psychotic Disorders.” Schizophrenia Research, vol. 192, pp. 300–307.

Sheffield, J.M., Hill S.K., et al. (2017) “Transdiagnostic Associations Between Functional Brain Network Integrity and Cognition.” JAMA Psychiatry, vol. 74, no. 6, Jan. 2017, p. 605.

Eum, S. Hill S.K., et al. (2017). Cognitive Burden of Anticholinergic Medications in Psychotic Disorders.” Schizophrenia Bulletin, vol. 43, no. suppl_1.

Hochberger, W.C., Hill S.K., et al. (2016) “Unitary Construct of Generalized Cognitive Ability Underlying BACS Performance across Psychotic Disorders and in Their First-Degree Relatives.” Schizophrenia Research, vol. 170, no. 1, pp. 156–161.

Hanna, R.C., Hill S.K., et al. (2016) “Cognitive Function in Individuals With Psychosis: Moderation by Adolescent Cannabis Use.” Schizophrenia Bulletin, vol. 42, no. 6, pp. 1496–1503.

Reilly, J. L., Hill S.K., et al. (2016) “Impaired Context Processing Is Attributable to Global Neuropsychological Impairment in Schizophrenia and Psychotic Bipolar Disorder.” Schizophrenia Bulletin.

Rubin, Leah H., Hill S.K., et al. (2016) “Sex Differences in Associations of Arginine Vasopressin and Oxytocin with Resting-State Functional Brain Connectivity.” Journal of Neuroscience Research, vol. 95, no. 1-2, pp. 576–586.

Hill, S. K, et al. (2014) “Regressing to Prior Response Preference After Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings From the B-SNIP Study.” Schizophrenia Bulletin, vol. 41, no. 4, pp. 940–950.

Ethridge, L. E., Hill S.K., et al. (2014) “Behavioral Response Inhibition in Psychotic Disorders: Diagnostic Specificity, Familiality and Relation to Generalized Cognitive Deficit.” Schizophrenia Research, vol. 159, no. 2-3, pp. 491–498.

Roseberry, JE, & Hill, SK. (2014). Limited practice effects and evaluation of expectation of change: MATRICS consensus cognitive battery. Schizophrenia Research, 159, 188-192.

Rubin, Leah H., Hill S.K., et al. (2014) “Reduced Levels of Vasopressin and Reduced Behavioral Modulation of Oxytocin in Psychotic Disorders.” Schizophrenia Bulletin, vol. 40, no. 6, pp. 1374–1384.

Reilly, J. L., Hill S.K. et al. (2013) “Elevated Antisaccade Error Rate as an Intermediate Phenotype for Psychosis Across Diagnostic Categories.” Schizophrenia Bulletin, vol. 40, no. 5, pp. 1011–1021.

Hill, S. K., et al. (2013) “Neuropsychological Impairments in Schizophrenia and Psychotic Bipolar Disorder: Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) Study.” American Journal of Psychiatry, vol. 170, no. 11, 2013, pp. 1275–1284.

Hill, S. K., Bjorkquist, O., Carrathers, T., Roseberry, J. E., Hochberger, W., and Bishop, J. (2013). Sequential Processing Deficits in Schizophrenia: Relationship to Neuropsychology and Genetics. Schizophrenia Research.

Hill, S.K., Griffin, G.B., Houk, J.C., & Sweeney, J.A. (2011). Differential effects of paced and unpaced responding on delayed serial order recall in schizophrenia. Schizophrenia research, 131, 192-197. 

Hill, S.K., Griffin, G.B., Miura, T.K., Herbener, E.S., & Sweeney, J.A. (2010). Salience of working memory maintenance and manipulation processing in schizophrenia. Psychological Medicine, 40, 1979-1986. 

Hill, S.K., Bishop, J.R., Palumbo, D, & Sweeney, J.A. (2010). The effect of second generation antipsychotics on cognition: Current issues and future challenges. Expert Reviews of Neurotherapeutics, 10(1), 43-57.

Hill, S.K., Reilly, J.L., Harris, M.S.H., Rosen, C., Marvin, R.W., DeLeon, O., & Sweeney, J.A. (2009). A comparison of neuropsychological dysfunction in first-episode psychosis patients with unipolar depression, bipolar disorder, and schizophrenia. Schizophrenia Research, 113, 167-175.

Hill, S.K., Reilly, J.L., Harris, M.S.H., Khine, T., & Sweeney, J.A. (2008). Oculomotor and neuropsychological effects of antipsychotic treatment for schizophrenia. Schizophrenia Bulletin, 34, 494-506.

Hill, S.K., Sweeney, J.A., Hamer, R.M., Keefe, R.S.E., Perkins, D.O., Gu, H., McEvoy, J.P., & Lieberman, J.A. (2008). Efficiency of the CATIE and BACS neuropsychological batteries in assessing cognitive effects of antipsychotic treatments in schizophrenia. Journal of the International Neuropsychological Society, 14, 209-221.

Hill, S.K., Harris, M.S., Herbener, E.S., Pavuluri, M., & Sweeney, J.A. (2008). Neurocognitive allied phenotypes of schizophrenia and bipolar disorder. Schizophrenia Bulletin, 34, 743-759.

In press publications:

Alliey-Rodriguez N, Grey TA, Shafee R, Padmanabhan J, Tandon N, Klinger M, Spring J, Coppes L, Reis K, Keshavan MS, Gage D, McCarroll S, Bishop JR, Hill SK, Reilly JR, Lencer R, Clementz B, Buckley B, Meda S, Narayanan B, Glahn D, Pearlson G, Ivleva E, Tamminga C, Sweeney JA, Curtis D, Keedy S, Badner J, Liu C, Gershon ES. (in press). Common variants of NRXN1, LRP1B and RORA are associated with increased ventricular volumes in psychosis - GWAS findings from the B-SNIP deep phenotyping study. 

Hill SK, Keefe RSE, & Sweeney JA. (in press). Cognitive biomarkers of Psychosis. In CA Taminga, J van Os, EI Ivleva, & U Reininghaus (Eds.). Psychosis. Oxford University Press.