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Stephanie Wu, DPM

Professor, & Associate Dean of Research, Director of CLEAR

Dr. Stephanie Wu is the Associate Dean of Research, Professor, Department of Podiatric Surgery and Applied Biomechanics, Professor, Center for Stem Cell and Regenerative Medicine, and Director, Center for Lower Extremity Ambulatory Research (CLEAR) for Dr. William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science. Dr. Wu devotes significant time to CLEAR’s fellowship program, international fellowship program, and Scholl’s Masters in wound healing program which is an international collaboration with Cardiff University. For her efforts in education, Dr. Wu has received many awards at Rosalind Franklin University including the Dean’s Award and the Lawrence R. Medoff Award for Outstanding Performance in Research, Teaching, and Clinical Practice. Dr. Wu led the effort in helping secure podiatry’s first NIH T-35 training grant for the training of future podiatric researchers at Dr. William M. Scholl College of Podiatric Medicine. In addition to her clinical and university duties Dr. Wu is a highly sought after lecturer at national and international forums.

Curriculum Vitae

Research

AREAS OF RESEARCH INTEREST

  1. Stem Cell and Tissue Regeneration
  2. Biofilms and wound Bioburden
  3. Activity monitoring and modulation in persons at high risk for diabetic foot ulceration and amputation
  4. Offloading the Diabetic Foot
  5. Risk factors for lower extremity complications in diabetes mellitus
  6. Proactive prevention of lower extremity complications of diabetes
  7. Diabetic Foot Infection
  8. The effect of diabetes on lower extremity mobility and function
  9. Footwear and insoles to prevent ulceration and reulceration in high risk diabetic patients
  10. Classification of risk factors for lower extremity amputation in diabetes mellitus
  11. Diabetic foot surgery: Classification/Outcomes
  12. Epidemiology of diabetes-related lower extremity amputations in minorities
  13. Diagnosis and management of acute Charcot’s arthropathy
  14. Infrared dermal thermometry of the high-risk diabetic foot
  15. The viscoelastic properties of skin

Research

Publications

Books and/or Chapters:

Bader M. Alavi A, Wu SC, Sibbald RG, Giovinco N, Armstrong DG, “Questions and Answers in Diabetic Foot Infections”, Diabetic Foot Infections, Guragon Nature Publishing / Macmillan, 2014

Bader M. Alavi A, Wu SC, Sibbald RG, Giovinco N, Armstrong DG, “Case Studies in Diabetic Foot Infections”, Diabetic Foot Infections, Guragon Nature Publishing / Macmillan, 2014

Armstrong DG, Bevilacqua, NJ, Wu SC. “Offloading Foot Wounds in People with Diabetes”, in Krasner DL, Chronic Wound Care: The Essentials (CWCE), 4th Ed., Philadelphia, Health Management Publications, 2014

Wu SC, DG, Armstrong “”Diabetic Foot Ulcers, Pathogenesis, Assessment, and Prevention” Diabetic Foot Infection, MS Bader, A Alavi, S Wu, p.15-36 ISBN: 978-93-80780-60-3, 1st Edition, MacMillan Medical Communications, Nature Publishing Group, 2013

Bader M. Alavi A, Wu SC, Sibbald RG, Giovinco N, Armstrong DG, “Diabetic Foot Infections”, Guragon Nature Publishing / Macmillan, 2013

Wu SC, Armstrong DG.  “Offloading the Diabetic Foot Wound”, in “Clinical Care of the Diabetic Foot, 2nd Edition” American Diabetes Association, Alexandria, MD, July, 2010

Armstrong DG, Wu SC, Crews RT, “Practical Strategies for Debridement, Off-Loading and Healing the Diabetic Foot Wound, in Rodriguez HE, Pearce WH, and Yao JST “The Ischemic Extremity: New Findings and Treatment”, Shelton Connicut, USA, People’s Medical Publishing, 265-272, 2010

Armstrong DG, Bevilacqua, NJ, Wu SC. “Offloading Foot Wounds in People with Diabetes”, in Krasner DL, Sibbald RG, and Rodeheaver G eds, Chronic Wound Care: A clinical source book for healthcare professionals, 4th Ed., Philadelphia, Health Management Publications, 2007

Wu SC, Armstrong DG, Lavery LK, Harkless LB. “Assessment of the Diabetic Foot”, in Diabetic Foot:  Medical and Surgical Treatment, 2nd edition, edited by Veves, Giurini, Lo Gerfo, Harvard University, published by Humana Press 2006

Armstrong DG, Wu SC, Crews RT. Practical Strategies for Debridement, Offloading and Healing the Diabetic Foot Wound, in Pearce WH, Matsumura JS, and Yao JST, “Trends in Vascular Surgery”, Evanston, IL, USA, Greenwood Academic, 461-472, 2006

Wu SC, Armstrong DG, Diabetic Foot syndrome II in Willy C “The Theory and practice of Vacuum Therapy Scientific Basis, Indications for Use, Case Reports, Practical Advice”, Altursried-Krugzell, Gerrmany, lindqvist book publishing ulm, 334-335, 2006

Wu SC, Armstrong DG, Prevent Skin damage due to the Trac-Pad Connector in Willy C “The Theory and practice of Vacuum Therapy Scientific Basis, Indications for Use, Case Reports, Practical Advice”, Altursried-Krugzell, Gerrmany, lindqvist book publishing ulm, 354, 2006

Armstrong DG, Wu SC, Crews RC, “New Casting Techniques: Introduction to the ‘Instant Total Contact Cast’”, in Boulton AJM, Cavanagh PR and Rayman G, “The Foot in Diabetes, 4th Ed, Chichester, Wiley & Sons, 350-354, 2006

Armstrong DG, Wu SC, Crews RC, “Algorithms for Assessing Risk for Ulcerations and Amputations”, in Boulton AJM, Cavanagh PR and Rayman G, “The Foot in Diabetes, 4th Ed, Chichester, Wiley & Sons, 431-439, 2006

Armstrong DG, Wu S.  “Offloading”, in “Clinical Care of the Diabetic Foot” American Diabetes Association, Alexandria, March, 2004

Wu S, Armstrong DG, Lavery L.  “Offloading”, in Diabetes Handbook, International Diabetes Federation, 2004

Peer Reviewed Publications:

Fejfarová,V Jirkovská A, Dragomirecká E, Game F, Bém R, Dubský M, Wosková V, Křížová M, Skibová J, Wu S, “Does the diabetic foot have a significant impact on selected psychological or social characteristics of patients with diabetes mellitus?” J Diabetes Res. 2014;2014:371938. Doi: 10.1155/2014/371938. Epub 2014 Mar 25.

Armstrong DG, Issac AL, Bevilacqua NC, Wu SC. “Offloading Foot Wounds in People with Diabetes”, Wounds. 2014;26(1):13-20

Kirsner RS, Bohn G, Driver VR, Mills JL, Nanney LB, Williams ML, Wu SC, “Human Acellular Dermal Wound Matrix: Literature Review and Clinical Experience”, Int Wound J. 2013 Nov 28

Wu SC, Skratsky MK, Andersen CA, “The Evolution of Negative Pressure Wound Therapy (NPWT): A Review of Science, Available Devices, and Evolution in the Usage of NPWT” Surg Technol Int. 2013 Aug 23;XXIII. pii: sti23/20

Baish R, Grewal G, Wu SC, Humble N, Jarrett B, Najafi B “Objective Assessment of Custom-Made Orthoses Benefit In Improving Balance Among Figure Ice-Skaters” Footwear Science, Jul 9, 2013 5: Supplement 1, S126-S127.

Crews RT, Yalla S, Fleischer A, Wu SC, “A Growing Troubling Triad: Diabetes, Aging and Falls”, J Aging Res. 2013;2013:342650. doi:10.1155/2013/342650

Wu SC, Crews RC, Najafi B, Rivera NS, Minder JL, Andersen C, “Safety and efficacy of mild compression (18-25mmHg) therapy in patients with diabetes and lower extremity edema”, J Diabetes Sci Technol. 2012 May 1;6(3):641-7

Wu SC, Marston W, Armstrong DG “Wound Care: The Role of Advanced Wound Care Modalities”, J Am Podiatr Med Assoc. 2010 Sep-Oct;100(5):385-94

Wu SC, Marston W, Armstrong DG “Wound Care: The Role of Advanced Wound Care Modalities”, J Vasc Surg. 2010 Sep;52(3 Suppl):59S-66SBecker JH, Wu SC “Fever – An Update”, J Am Podiatr Med Assoc. 2010 Jul-Aug;100(4):281-90

Najafi B, Horn D, Marclay S, Crews RT, Wu S, Wrobel JS. “Assessing postural control and postural control strategy in diabetes patients using innovative and wearable technology” J Diabetes Sci Technol. 2010 Jul 1;4(4):780-91

Bowling FL, Metcalfe SA, Wu S, Boulton AJ, Armstrong DG. “Liquid silicone to mitigate plantar pedal pressure: a literature review” J Diabetes Sci Technol. 2010 Jul 1;4(4):846-52.

Wu SC, Jensen J, Weber A, Robinson D, Armstrong DG “Use of Pressure Offloading Devices in Diabetic Foot Ulcers: Do We Practice What We Preach“ Diabetes Care. 2008 Nov;31(11):2118-9. Epub 2008 Aug 11

Kline EE, Crews RT, Wu SC, Wrobel JS, Armstrong DG “The CLEAR Cleat: Aerobic Activity Facilitator for Persons at high-risk for Lower Extremity Amputation”, J Am Podiatr Med Assoc. 2008 Jul-Aug;98(4):261-7

Wu SC, Crews RT, Zelen C, Wrobel J, Armstrong DG “Evaluation of Chlorhexadine Gluconate Impregnated Polyurethane Dressing Against Percutaneous Device Related Skin Colonization and Local Infections: the ChIPPS Pilot Trial“,Int Wound J. 2008 Jun;5(3):416-22. Epub 2008 Jun 1.

Wu SC, Armstrong DG “Clinical Outcome of Diabetic Foot Ulcers Treated Negative Pressure Wound Therapy and Transition from Acute Care to Home Care” IWJ, 5 (suppl. 2):10-16, Jun 2008

Wu SC “Evolution and Progression of Arterial Occlusive Disease in Patients with Diabetes”, Journal of Vascular Ultrasound, 32(1):21-26, 2008

Nelson DL, Wu SC, Armstrong DG “Delayed Primary Closure of Diabetic Foot Wounds Using the Dermaclose RC Tissue Expander” The Foot and Ankle Journal 1(2):3, 2008

Wu SC, Crews RT, Armstrong DG, “The Prevalence of Onychomycosis within Diabetic Feet at High Risk for Ulceration”, Clin in Dermatology, submitted November, 2007

Martínez De Jesús FR, Ramos-De la Medina A, Remes-Troche JM, Armstrong DG, Wu SC, Lazaro Martinez JL, Beneit-Montesinos JV.  “Efficacy and safety of neutral pH superoxidised solution in severe diabetic foot infections”, Int Wound J. 2007 Dec;4(4):353-62. Epub 2007 Oct 22

Wu SC, Wrobel J, Armstrong DG “Assessing the Impact of Pharmacologic Intervention on the Quality of Life in Diabetic Peripheral Neuropathic Pain and Fibromyalgia” Pain Medicine, 2007 Sept;8(S2 Suppl):S33-S42

Wu SC, Armstrong DG “Algorithm for Assessing Risks for foot Ulcerations”, Health Care Guidelines, Institution for clinical Systems Improvement, Pan American Health Organization, published August, 2007

Wu SC, “Algorithm for Vascular Assessment in the Foot at Risks”, Health Care Guidelines, Institution for clinical Systems Improvement, Pan American Health Organization, published August, 2007

Wu SC, Armstrong DG “Surgical Treatment of Diabetic Foot Ulcers with Topical Negative Pressure Therapy” Topical negative pressure therapy: Science and Practice, Medical Education Limited, May, 2007

Wu SC, Driver VR, Wrobel JS, Armstrong DG “Foot ulcers in the diabetic patient, prevention and treatment” Vasc Health Risk Manag. 2007;3(1):65-76

Wu SC, Driver VR, Armstrong DG “Vascular Problems in the Diabetic Foot” Journal for Vascular Ultrasound 2006 Dec; 30(4) 203-12

Wu SC, Driver VR, Armstrong DG “Negative Pressure Wound Therapy:  Current Procedure and Practice” Expert Review of Dermatology 2006 Oct;1(5)701-7

Armstrong DG, Lavery LA, Frykberg RK, Wu SC, Boulton AJM, “Validation of a Diabetic Foot Surgery Classification”, International Wound J. 2006 Sep;3(3):240-6.

Wu SC, Armstrong DG “The role of activity, adherence, and off-loading on the healing of diabetic foot wounds.” Plast Reconstr Surg. 2006 Jun;117(7 Suppl):248S-253

SJirkovska A, Boucek P, Wu S, Hosova J, Bem R, Fejfarova V, Skibova J, “Power Spectral Analysis of Heart Rate Variability in Patients with Charcot’s Neuroarthropathy, J Am Podiatr Med Assoc. 2006 Jan-Feb;96(1):1-8.

Wu SC, Crews R, Armstrong DG, “The pivotal role of offloading in the management of neuropathic foot ulceration” Curr Diab Rep. 2005 Dec;5(6):423-9

Wu S, Armstrong D, “Treatment, wound care and off-loading techniques in the management of the diabetic foot”, Diabetes Voice, November, Volume 50: Special Issue p.29-32, Nov. 2005

Martin BR, Sangalang M, Wu S, Armstrong DG. “Outcomes of Allogenic Matrix Therapy in Treatment of Diabetic Foot Wounds”, International Wound Journal, 2005 Jun; 2(2):161-165.

Armstrong DG, Holtz K, Wu S.  “Can the Use of a Topical Antifungal Nail Lacquer Reduce Risk for Diabetic Foot Ulceration? Results from a Randomized Controlled Trial”, International Wound Journal. 2005 June; 2(2):166-170.

Wu S, Armstrong DG.  “Risk Assessment of the Diabetic Foot and Wound”. International Wound Journal, 2:17-24, April 2005.

Armstrong DG, Lavery LA, Wu S, Boulton AJM. “Evaluation of removable and irremovable cast walkers in the healing of diabetic foot wounds: a Randomized Controlled Trial” Diabetes Care. 2005 Mar; 28(3):551-4.

Non-Peer Reviewed Publications:

Brannick B, Engelthaler M, Jadzak J, Wu SC, “Continuous Diffusion of Oxygen Therapy In the Treatment of A Chronic, Painful Venous Leg Ulcer”, Podiatry Today, 2014 Oct; Online Case Study

Khademi S, Holand B, Yorath M, Wu SC “When Surgeons Uncover A Verrucous Carcinoma Following Delayed Healing of A Transmetatarsal Amputation”, Podiatry Today, 2014 Sept; 27(9) Online Case Study

Campbell T, Woodard Q, Wu SC, “Should We Use Antimicrobial Dressings For Clean, Uninfected Wounds”, Podiatry Today, 2013 Dec; 26(12):54-60

Ramos J, Wu S “Role of Epidermal Skin Grafting in the Treatment of Lower Extremity Wounds” Podiatry Management, November/December 2013

Wu SC, Skratsky M, “Debridement and the Current State of Play” Podiatry Management, 2012 Nov/Dec;31(9):145-153

Skratsky M, Wu SC, “A Closer Look at the Efficacy of Bioengineered Alternative Tissues for DFUs” Podiatry Today, 2012 Oct;25(10):50-58

Rivera NS, Wu SC, “A Guide for Compression Dressing for Venous Ulcers” Podiatry Today 2012 Feb;25(2):61-9

Wu SC, “Updates in Diabetic Peripheral Neuropathy” Podiatry Management Nov/Dec 2011; 30(9):157-163

Rivera NS, Wu SC, “Keys to Effective Wound Dressing Selections”, Podiatry Today, 2011 Aug; 24(8):36-43

Fernan DA, Wu SC “New Developments in Diabetes”, Podiatry Today 24(1):16-20, Jan 2011

Wu SC “A Closer look at the Impact of Chronic Wound Bioburden” Podiatry Today 2010 May;23(4):36-42

Wu S, “Essential Insight in the Management of Painful Diabetic Neuropathy”, Podiatry Today 2009 Nov;22(10):60-6

Wu SC, Maloney R “New Treatments for Ischemic Wounds”, August, 2009, Podiatry Management

Jirkovska A, Wu SC, Riha SD, Bulejcik J, Varga M, Sixta B, Matia I, Hackajlo D, et al “syndrome diabeticke nohy”, Bulletin HPB chirurgie, 2008

Wu SC “Injectable Silicone to Mitigate Plantar Pedal Pressure”, Podiatry Today 21(9):62-70, August 2008.

Wu SC, Maloney R “Laser Therapy: A Possible New Light on Wound Healing”, Podiatry Management 27(6):105-10, Aug. 2008

Nelson DL, Wu SC, Armstrong DG “Delayed Primary Closure of Diabetic Foot Wounds Using the Dermaclose RC Tissue Expander” Podiatry Management 27(2):133-8, 2008

Ali YA, Crews RT, Wu SC, Armstrong DG “VCC – The Marriage of Modern Technologies and Common Sense”, O&P Almanac, March, 2008

Wu SC “New Modalities to Help Predict Wound Healing”, Podiatry Today 20(7):55-64, July, 2007

N Bevilacqua, S Wu, “Surgical Considerations for Patients with Diabetes”, Podiatry Management, June, 2007

Wu SC, “Maggots – Nature’s helpers to heal wounds”, InMotion publication, American Amputee Coalition, Volume 17 · Issue 3 · May/June 2007

Wu SC, Bevilacqua NJ, Rogers, LC, Armstrong DG. “Tissue Volumizing Agents: Can We Create an Internal Orthotic?” Podiatry Today 19(10):58-63, October 2006

Wu S, “Updates in Wound Debridement”, Podiatry Management, August, 2006

Wu SC “Case Studies in Treating Painful Diabetic Neuropathy”, Podiatry Today 19(8):86-93, August, 2006

Wu SC, Lavery LA, Armstrong DG “Closing Difficult Wounds:  Current Concepts In Negative Pressure Wound Therapy”, Podiatry Today 19(3):44-56, March, 2006

Wu S, Armstrong D “Updates in Diabetic Neuropathy”, Podiatry Management, November, 2005 

Wu S, Yoon H, Armstrong D, “Combined use of negative pressure wound therapy with advanced wound healing modalities”, Podiatry Today, 18(9):18-22, September, 2005.

Zelen C, Weinraub G, Wu S, “Use of External Fixation in Forefoot Surgery“, Podiatry Management, p.187-94, August, 2005.

Wu S, “Current and emerging treatments for diabetic neuropathy”, Podiatry Today, 18(3):66-72, March, 2005.

Wu NCBI Bibliography

Teaching

Clinical teaching to the following students:

  • Scholl College (SCPM)
  • Chicago Medical School (CMS)
  • Interprofessional students (RFUMS)

Didactic teaching in the following courses:

  • PAPB501 Understanding & Implementing Clinical Research
  • PSUR 602 General Surgical Principles and Anesthesiology
  • PBBS 503 Structure and Function

Didactic teaching of 8 week summer research course to the following students:

  • Scholl Summer Research Fellowship students
  • Chicago Medical School summer research students