Cellular and Molecular Pharmacology

Medical Courses

MCMP 600A, B, C - Foundations of Medical PharmacologyThe subject matter is covered in lectures, conferences and tutorials. The mechanism of action of drugs at subcellular, molecular and biochemical levels, and factors affecting drug absorption, distribution, metabolism and excretion are discussed. In addition, pharmacogenetics, drug interactions, therapeutic uses, contraindications and side effects, as well as toxicology of selected compounds are presented. Dr. Snyder and Faculty. MCMP 600A - Fall Quarter, three lecture hours per week (3 units).MCMP 600B - Winter Quarter, four lecture hours per week (4 units)MCMP 600C - Spring Quarter, four lecture hours per week (4 units)

MCMP 613 - Principles of Drug Action & TherapeuticsStudents taking this elective course are expected to gain a comprehensive view of the science of pharmacology in terms of its basic concepts and principles. We will discuss the general pharmacokinetic and pharmacodynamic principles governing the action of the main classes of drugs; they will include both “defined molecule” agents as well as select representatives of the rapidly expanding area of biologicals. Emphasis will be placed in understanding the relationship between drug dose, host factors and therapeutic response. Two lecture hours per week (1 unit). Dr. Mosnaim and Faculty.

MCMP 615 - Regulation of Gene Expression by Drugs of Abuse (Research)Drugs of abuse such as cocaine cause altered expression of genes in neurons of brain systems that are involved in the generation of motivated behavior. Such changes in gene regulation are part of the neuronal basis for drug addiction and dependence. Our research focuses on the effects of drugs of abuse on gene regulation in the basal ganglia and related forebrain systems. We mainly investigate how psychostimulant drugs affect the expression of genes that encode peptide neurotransmitters, transmitter-related enzymes, receptors, ion channels and transcription factors and how such neuronal changes alter basal ganglia output and behavior. These studies contribute to our under-standing of the molecular and cellular changes underlying drug addiction. The offered course is part of this research. Dr. Steiner.

MCMP 618 - Anatomy and Function of Brain Reward Circuits (Research)Anatomical studies will be performed in rodent models whose brain activity will have been previously established using neurophysiological techniques. Students will learn a variety of skills, such as histological techniques, bright-field and fluorescent microscopy, and statistical and data analysis. Finally, students will attend weekly lab meetings, where they will interact with other lab members, present data, and familiarize themselves with research methods in health-related sciences. Dr. Marinelli.

Graduate Courses

GCMP 500 - Electrophysiology Journal ClubThe purpose of the electrophysiology journal club is to facilitate the understanding and discussion of electrophysiological data, from published papers to preliminary/exciting yet unpublished observations from different electrophysiology laboratories in our school. Dr. Tseng.

GCMP 502 - Journal Club in Cellular and Molecular Pharmacology Consists of informal presentation and discussion of current and novel literature in pharmacology. May be repeated for credit. One hour every two weeks, Tuesdays at noon. Dr. Rosenkranz.

GCMP 509 - Seminar in Pharmacology Internationally-recognized scientists present their most recent research. Students meet for lunch with the speakers, allowing for informal interactions. May be repeated for credit. Dr. Tseng.

GCMP 535 - Research in Pharmacology - ThesisThis designation is utilized for students who have passed their candidacy exam, and are performing thesis work/research in pharmacology. Credit hours to be arranged with thesis mentor.  Faculty.

GCMP 539 - Research in Pharmacology - IntroductionThis designation is utilized for students who have yet to pass their candidacy exam, and are performing research in pharmacology. Credit hours to be arranged with research mentor.  Faculty.

GCMP 540 - Principles in Pharmacokinetics and PharmacodynamicsLectures focus on basic principles in pharmacokinetics and pharamcodynamics. Problem-solving exercises and scholarly publications will accompany discussion lectures.2 hours/week.  Faculty

GCMP 601 - Neuropharmacology I Lectures present a comprehensive overview of the cellular foundations of neuropharmacology, techniques used in neuropharmacology, and experimental design. Principles of excitable membranes and ion channels will be discussed. Subject matters are covered in lectures and with interactive problem-solving approaches. These lectures will provide a background to the topics covered in GCMP602 Neuropharmacology II. 2 hours/week. Dr. Mosnaim.

GCMP 602 - Neuropharmacology II Lectures focus on neurotransmitter systems and how these participate on specific behaviors and disease states. Final lecture will integrate basic neuropharmacology research with the translational aspects of drug discovery. Scholarly publications will accompany discussion lectures. 2 hours/week. Dr. Mosnaim.

GCMP 605 - Pharmacology Core This course will introduce students to the basic principles of drug action. The first quarter will cover basic principles of the autonomic drugs and the therapeutic uses, side effects, and interactions of prostaglandins, NSAIDs, and central nervous system agents. The second quarter will continue the study of selected drug categories, including antimicrobials, anti cancer drugs, general and local anesthetics, cardiac drugs, and sedative/hypnotics. The third quarter will continue with drug categories that include endocrine and metabolic modulators, and treatment of asthma. Subject matters are covered in lectures, tutorials, and discussions. 2 hours/week. Dr. Snyder.

GCMP 608 - Research Skills: Beyond the Bench This course will review the skills required for a successful career in academic research.  It will provide tools that will help students develop such skills.  Modules are geared towards real-life experiences that students will encounter while performing scientific research in academic settings.  The course will also increase professionalism and communication skills.  The course has four modules and focuses on 1) meetings, 2) manuscripts, 3) grants, and 4) administrative research duties. Dr. Marinelli.

GCMP 700 - Teaching in PharmacologyPart of our mission is to prepare students for academic and educational positions. Students will be trained in teaching strategies and will serve as facilitators in the Medical Pharmacology small-group problem-solving sessions, and as lecturers in the Basic Biomedical Science pharmacology review sessions. Dr. Snyder.

Podiatry Course

PBBS 601A&B - Pharmacology (Scholl College of Podiatry)This course is a comprehensive presentation of medical pharmacology. The general principles of drug disposition including drug absorption, distribution, metabolism, elimination and pharmacokinetics are covered as well as pharmacodynamics of major drug groups. Emphasis is on mechanism of drug action, uses, adverse effects, contraindications and clinically important drug interactions of particular utility to the podiatrist. Additionally, clinical applications of pharmacologic principles pertinent to the podiatrist are presented. Dosage is not emphasized unless specifically stated by the instructor.

 

Other Courses of Interest || Multidisciplinary Courses of Interest

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