Cellular and Molecular Pharmacology

GIGP-508 Ethics and Regulatory Issues in Biomedical Research (2.00 cr.)
REQUIRED for IGPBS - This course covers most of the major issues related to the responsible conduct of research in the biomedical sciences, including: overt falsification, fabrication, plagiarism (FFP); authorship and publication guidelines; conflict of interest; mentor/trainee responsibilities, and human subject research. Online component includes certification for using radioisotopes and using animals in research. Lecture, discussions, and online modules. Winter quarter. Coordinated by Dr. Eliot.

GIGP-504 Neuroscience Elective for IGPBS (7.00 cr.)
This course provides a broad introduction to modern neuroscience, emphasizing: 1) cellular neuroscience, including the neurochemistry of transmitters and receptor function; 2) systems neuroscience, encompassing sensory, motor, affect, memory, language, and other high cognitive functions; 3) human neuroanatomy, taught using a combination of atlases, realistic models, cadaver brains, and interactive computer programs; and 4) clinical neuroscience, focusing on the neurobiological basis of major neurological and psychiatric disorders. Lectures will be supplemented with discussions of recent journal articles. Lecture, lab and discussion. Spring. Coordinated by Dr. Eliot.

GNSC-505 Human Brain Dissection (1.00 cr.) An intensive short course, where students will carry out a detailed dissection of a human cadaver brain. This dissection will expose them to all the major areas of the human forebrain, brainstem, and cerebellum, including major fiber tracts subcortical nuclei, and their connections to brainstem and cortical structures. Special emphasis will be placed on human limbic structures and the circuitry underlying emotion, addiction, and other psychiatric disorders. Dr. Eliot, Fall quarter, 1 credit. Lab Only.

GNSC-600 Neurophysiology (2.00 cr.)
A thorough review of neurophysiological function, including the ionic basis of the neuronal membrane potential and action potentials, pre- and post-synaptic signaling, signal transduction, cable properties, and synaptic plasticity. Fall Quarter, two hours per week. Coordinated by Dr. Stutzmann. Seminar/Discussion

GNSC-605 Techniques in Microscopy (1.00 cr.)
A comprehensive instruction to state-of-the-art microscopy and design-based stereology. Lectures cover the fundamentals of tissue preparation and staining, microscopy, digital imaging and confocal stereology. Fall Quarter, 1 credit, Dr. Peterson. Lecture-Lab.

GNSC-606 Neurodegeneration (2.00 cr.)
Mechanisms of brain death and neuronal degeneration resulting from chronic or acute diseases and their prospects for recovery. Topics include the clinical features and animal models of traumatic brain injury, stroke, spinal cord injury, Parkinson's, Alzheimer's and Huntington's diseases. Spring Quarter, two hours per week. Coordinated by Drs. Ariano and West. Seminar/Discussion.

GNSC-607 Neuronal Signaling (2.00 cr.)
This course covers intracellular signaling mechanisms including G proteins, phosphoinositides, cyclic nucleotides, calcium, serine and threonine phosphorylation, and tyrosine phosphorylation. Faculty will present basic information on each topic. Students are responsible for leading discussions based on the text and journal articles. Winter Quarter, two hours per week. Dr. Wolf. Seminar/Discussion.
Life in Discovery
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