Publications
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Havens, MA, Reich, AA, Duelli, DM, Hastings, ML. 2012. Biogenesis of mammalian microRNAs by a non-canonical processing pathway. Nucleic Acids Res. (in press).
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Kim, DJ, Linnstaedt, S, Palma, J, Park, JC, Ntrivalas, E, Kwak-Kim, JYH, Gilman-Sachs, A, Beaman, K, Hastings, ML, Martin, JN, and Duelli, DM. 2012. Plasma components affect accuracy of circulating cancer-related microRNA quantitation. J. Mol. Diagn. 14: 71-80.
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Vorlova, S, Rocco, G, LeFave, CV, Jodelka, FM, Hastings, ML, Henke, E, and Cartegni, L. 2011. Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation. Mol. Cell. 43: 927-939.
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Bruno, A, Huang, J, Bennett, DA, Marr, R, Hastings, ML, Stutzmann, GE. 2011. Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer’s disease. Neurobiol. Aging, in press.
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Pigati, L, Yaddanapudi, S, Iyengar, R, Kim, DJ, Hearn, S, Danforth, D, Hastings, ML, Duelli, DM. 2010. Selective release of microRNA species from normal and malignant mammary epithelial cells. PLoS One. http://dx.plos.org/10.1371/journal.pone.0013515.
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Jodelka, FM, Ebert, AD, Duelli, DM, Hastings, ML. 2010. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum Mol Genet, 19: 4906-4917.
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Salato, VK, Rediske, NW, Zhang, C, Hastings, ML, Munroe, SH. 2010. An exon splicing enhancer within a bidirectional coding sequence regulates alternative splicing of an antisense mRNA. RNA Biology, 7: 179-90.
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Hastings, ML, Berniac, J, Liu, YH, Abato, P, Jodelka, FM, Barthel, L, Kumar, S, Dudley, C, Nelson, M, Larson, K, Edmonds, J, Bowser, T, Draper, M, Higgins, P, Krainer, AR. (2009) Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy. Science Translational Medicine, 1: 5ra12.
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Hastings, ML, Sachidanandam, R. 2008. Evolutionary conservation of splice sites. In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0020782.
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Martins de Araujo, M, Bonnal, S, Hastings, ML, Krainer, AR, Valcarcel, J. 2009. Differential 3’ splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP. RNA, 15: 515-23.
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Zhang, C, Hastings, ML, Krainer, AR, Zhang, MQ. 2007. Dual-specificity splice sites function alternatively as 5’ and 3’ splice sites. Proc Natl Acad Sci USA, 104: 15028-33.
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Allemand, E, Hastings, ML, Murray, MV, Myers, MP, Krainer, AR. 2007. Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid binding protein YB-1. Nature Struct Biol, 14: 630-8.
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Hastings, ML, Allemand, E, Duelli, DM, Myers, MP, Krainer, AR. 2007. Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). PLoS ONE, 2: e538.
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Cartegni, L, Hastings ML, Calarco, JA, de Stanchina, Krainer, AR. 2006. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet, 78: 63-77.
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Sheth, N, Roca, X, Hastings, ML, Roeder, T, Krainer, AR, Sachidanandam, R. 2006. Comprehensive splice-site analysis using comparative genomics. Nucleic Acids Res, 34: 3955-67.
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Hastings, ML, Resta, N, Traum, D, Stella, A, Guanti, G, Krainer, AR. 2005. An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites. Nat Struct Mol Biol, 12: 54-9.
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Hastings, ML, Krainer, AR. 2001. Pre-mRNA splicing in the new millennium. Curr Opin Cell Biol, 13: 302-9.
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Hastings, ML, Wilson, CM, Munroe, SH. 2001. A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA. RNA, 7: 859-74.
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Hastings, ML, Krainer, AR. 2001. Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway. RNA, 7: 471-82.
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Hastings, ML, Ingle, HA, Lazar, MA, Munroe, SH. 2000. Post-transcriptional regulation of thyroid hormone receptor expression by cis-acting sequences and a naturally occurring antisense RNA. J Biol Chem, 275: 11507-13.
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Hastings, ML, Milcarek, C, Martincic, K, Peterson, ML, Munroe, SH. 1997. Expression of the thyroid hormone receptor gene, erbAalpha, in B lymphocytes: alternative mRNA processing is independent of differentiation but correlates with antisense RNA levels. Nucleic Acids Res. 25: 4296-300.
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Publications
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