Donghee Kim, Ph.D.

Professor, Physiology and Biophysics

Chicago Medical School
Building: RLE-3.341
Phone: 847-578-8356
Fax: 847-578-3265
Recent Publications

Kang DW, Kim D. TREK-1 and TRESK are two major background K channels in dorsal root ganglion neurons. Am J Physiol Jul;291(1):C138-46, 2006.

Kang DW. Han JH, Kim D. Mechanism of inhibition of TREK-2 by acetylcholine via Gq. Am J Physiol Oct; 291(4):C649-56, 2006.

Kang, DW, Choe C, Cavanaugh EJ, Kim D. Properties of Single TREK-2 (K2P10.1) Channels Expressed in Mammalian cells. J. Physiol. 583.1: 57-69, 2007.

Kim D, Cavanaugh EJ. Requirement of a cytosolic factor for activation of TRPA1: role of inorganic polyphosphates. J. Neurosci. 27:6500-6509, 2007.

Cavanaugh EJ, Simkin D, Kim D. Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol, and Ca reveals different functional channel states. Neuroscience 154:1467-1476, 2008.

Kim D, Cavanaugh EJ, Simkin D. Inhibition of transient receptor potential A1 by phosphatidylinositol-4,5-bisphosphate. Am. J. Physiol. Cell Physiol. 295:C920C99, 2008.

Cruz-Orengo L, Dhaka A, Heuermann RJ, Yong TJ, Montana MC, Cavanaugh EJ, Kim D, Story GM. Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. Molecular Pain 4:30 (1-9), 2008.

Simkin D, Cavanaugh EJ, Kim D. Control of single channel conductance of K2P10.1 (TREK-2) by the amino terminus: role of alternative translation initiation. J. Physiol. 586.23, 5651-5663, 2008.

Kim D, Cavanaugh EJ, Kim I, Carroll JC. Heteromeric TASK-1/3 is the major oxygen-sensitive background K channel in rat carotid body glomus cells. J. Physiol. 587, 2963-2975, 2009.

Kang D, and Kim D. Mammalian K2P channel family. In: Structure and function of ion channels. Oxford University Press. Chapter 2, 2009.

Chen J, Kim D, Bianchi BR, Cavanaugh EJ, Faltynek CR, Kym PR, Reilly RM. Pore dilation occurs in TRPA1 but not in TRPM8 channels. Molecular Pain 5:3-12, 2009.

Kim D, Papreck JR, Kim IS, Donnelly DF, Carroll JL. Changes in oxygen sensitivity of TASK in carotid body glomus cells during early postnatal development, Respiratory Physiol and Neurobiol, 177: 228-235, 2011.

Kim D, Kim IS, Papreck JR, Donnelly DF, Carroll JL. Characterization of the ATP-sensitive K+ channel in the rat carotid body glomus cells, Respiratory Physiol and Neurobiol, 177:245-255, 2011.

Papreck JR, Martin EA, Lazzarini P, Kang D, Kim D. Modulation of K(2P)3.1 (TASK-1), K (2P)9.1 (TASK-3), and TASK-1/3 heteromer by reactive oxygen species. Pflugers Archiv (European Journal of Physiology) Nov;464(5):471-80, 2012.

Kim D.  K(+) channels in O(2) sensing and postnatal development of carotid body glomus cell response to hypoxia. Respir Physiol Neurobiol. 2013 Jan 1;185(1):44-56.

Kang D, Hogan JO, Kim D.  THIK-1 (K2P13.1) is a small-conductance background K+ channel in rat trigeminal ganglion neurons. Pflugers Arch. 2013 Oct 1. [Epub ahead of print] PMID: 24081450

Chen J, Kang D, Xu J, Lake M, Hogan JO, Sun C, Walter K, Yao B, Kim D. Species differences and molecular determinant of TRPA1 cold sensitivity.  Nature Communications 2013;4:2501. doi:10.1038/ ncomms 3501.

Kim D, Kang DW, Martin EA, Kim IS, Carroll JL. Effects of modulators of AMP-activated protein kinase on TASK-like K+ channels and intracellular Ca2+ concentration in rat carotid body glomus cells. Respir Physiol Neurobiol. 195:19-26, 2014

Kang DW, Wang J, Hogan JO, Vennekens R, Freichel M, White C, Donghee Kim. Increase in cytosolic Ca2+ produced by hypoxia and other depolarizing stimuli activates a non-selective cation channel in chemoreceptor cells of rat carotid body.  J. Physiol (Lond). 2014




Life in Discovery
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