David M. Mueller, Ph.D.

Professor
Chicago Medical School
Biochemistry and Molecular Biology
Room: 3.116
Building: BSB
Phone: 847.578.8606
Fax: 847.578.3240
David.Mueller@rosalindfranklin.edu 
Publications
Arsenieva D., Symersky J., Wang Y., Pagadala V., Mueller D.M. (2010) Crystal structures of mutant forms of the yeast F1 ATPase reveal two modes of uncoupling, J Biol Chem. 2010 Sep 14. [Epub ahead of print] [pubmed]

Kabaleeswaran V., Shen H., Symersky J., Walker J.E., Leslie A.G., Mueller D.M. (2009) Asymmetric structure of the yeast F1 ATPase in the absence of bound nucleotides. J Biol Chem 284, 10546-10551. [pubmed]

Shen, H., Walters, D.E., and Mueller, D.M. (2008) Introduction of the Chloroplast Redox Regulatory Region In the Yeast ATP Synthase Impairs Cytochrome Oxidase, J. Biol. Chem. 283: 32937-32943. [pubmed]

Wang, Y., Singh, U., and Mueller, D.M. (2007) Mitochondrial Genome Integrity Mutations Uncouple the Yeast Saccharomyces cerevisiae ATP Synthase, J. Biol. Chem. 282, 8228-8236. [pubmed]

Kabaleeswaran, V., Puri, N., Walker, J.E., Leslie, A.G.W., Mueller, D.M. Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase (2006) EMBO J., 25, 5433-5442.[pubmed]

Puri, N., La-Zhang, N., Meier, S., and Mueller, D.M., (2005) Expression of bovine F1-ATPase with functional complementation in yeast Saccharomyces cerevisiae. J. Biol. Chem. 280, 22418-22424. [pubmed]

Mueller DM, Puri N, Kabaleeswaran V, Terry C, Leslie AG, Walker JE. (2004) Ni-chelate-affinity purification and crystallization of the yeast mitochondrial F1-ATPase. Protein Expr Purif. 37, 479-485. [pubmed]

Mueller DM, Puri N, Kabaleeswaran V, Terry C, Leslie AG, Walker JE. 2004) Crystallization and preliminary crystallographic studies of the mitochondrial F1-ATPase from the yeast Saccharomyces cerevisiae. Acta Crystallogr D Biol Crystallogr. 60(Pt 8), 1441-1444. [pubmed]

Paumard P, Vaillier J, Coulary B, Schaeffer J, Soubannier V, Mueller D.M., Brethes D, di Rago JP, Velours J., (2002) The ATP synthase is involved in generating mitochondrial cristae morphology. EMBO J. 21, 221-30. [pubmed]

Velours J, Vaillier J, Paumard P, Soubannier V, Lai-Zhang J, Mueller DM. (2001) Bovine coupling factor 6, with just 14.5% shared identity, replaces subunit h in the yeast ATP synthase. J Biol Chem. 276, 8602-7. [pubmed]

Mueller DM. (2000) Partial assembly of the yeast mitochondrial ATP synthase. J Bioenerg Biomembr. 32, 391-400. [pubmed]

Lai-Zhang, J. and Mueller, D.M. (2000) Complementation of the null mutants in the genes encoding the F1 ATPase with expression of the corresponding bovine cDNAs in yeast S. cerevisae, Eur. J. Biochem 267, 2409-2418. [pubmed]

Xiao, Y., Metzl, M. and Mueller, (2000) D.M. Partial uncoupling of the mitochondrial membrane by a heterozygous null mutation in the gene encoding the g- or d-subunit of the yeast mitochondrial ATPase J. Biol. Chem. 275, 6963-6968. [pubmed]

Yao, B.Y. and Mueller, D.M. (1999) The Role of the Amino-terminal b-barrel Domain of the a- and b- Subunits in the Yeast F1-ATPase J. Bioenerg. Biomemb. 31, 95-104. [pubmed]

Bakhtiari, N., Zhang, J.L., Yao,B., and Mueller, D.M., (1999) Structure/function of the b-barrel domain of the F1-ATPase in yeast Saccharomyces cerevisiae. J. Biol. Chem. 274, 16363-16639. [pubmed]

Lai-Zhang, J., Xiao, Y., and Mueller, David. M. (1999) Epistatic interactions of deletion mutants in the genes encoding the F1-ATPase in yeast S. cerevisiae

EMBO J. 18, 58-64. [pubmed]

Croopnick, J.B., Choi, H.C., and Mueller, D.M.(1998) The subcellular location of the yeast Saccharomyces cerevisiae homologue of the protein defective in the juvenile form of Batten disease. Biochem. Biophys. Res. Comm. 250, 335-341. [pubmed]

Sosa-Peiando, A., and Mueller, D.M. (1997) Mutagenesis of b-V198 in the F1-ATPase of yeast Saccharomyces cerevisiae and its role in binding nucleotide. Arch. Biochem. Biophys. 337, 27-33. [pubmed]

Mao, Y. and Mueller, D.M. (1997) Structural interactions of the oligomycin sensitivity conferring protein in the yeast ATP synthase, Arch. Biochem. Biophys. 337, 8-16. [pubmed]

Shen, H., Sosa-Peiando, A., and Mueller, D.M. (1996) Intragenic suppressors of P-loop mutations in the b-subunit of the mitochondrial ATPase in yeast Saccharomyces cerevisiae. J. Biol. Chem. 271, 11844-11851. [pubmed]

Shen,H.-g. Yao, B-y. and Mueller, D., (1994) Primary Structural Requirements of the Glycine-Rich ATP Binding Motif of the Yeast S. cerevisiae Mitochondrial F1-ATPase, J. Biol. Chem. 269, 9424-9428. [pubmed]
Life in Discovery
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