H.J.Kelly Oh, Ph.D.

Research Assistant Professor
Chicago Medical School
Room 3.229
Building: BSB
Phone: 847.578.3000 Extension 3363
Fax: 847.578.3253
kelly.oh@rosalindfranklin.edu
Research

The primary pathogenic event in Duchenne Muscular Dystrophy is muscle cell necrosis, which is followed by regenerative responses. We found that the loss of dystrophin in C. elegans causes a progressive muscle cell death as in mammals, and that the muscle cell death can be prevented by modulating signaling pathways. Currently, we are investigating roles of IGF-1 signaling and stress responses in dystrophic muscle cells.

Life in Discovery
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