Michael P. Sarras, Jr., Ph.D.

Chicago Medical School
Room L.407
Building: BSB
Phone: 847.578.3435
Fax: 847.578.3253
Articles published pertaining to current research program on the underlying mechanisms of Metabolic Memory in Diabetes that began in 2008 (of career total of 82 publications).

A. Peer Reviewed Articles:

Ansgar Olsen, Michael P. Sarras, Jr., and Robert Intine. Impaired limb regeneration in a Zebrafish model of Diabetes. J. Wound Healing and Tissue Regeneration. 2010, 18(5):532-42.

Ansgar S. Olsen, Michael P. Sarras Jr., Alexey Leontovich, and Robert V. Intine. The heritable transmission of diabetic metabolic memory in zebrafish correlates with DNA hypomethylation and aberrant gene expression. Diabetes. 2012, 61(2),485-91.

Robert V. Intine, Ansgar S. Olsen, and Michel P. Sarras Jr. A zebrafish model of diabetes mellitus and metabolic memory. JOVE, 2013, 72 (e50232).

Michael. P. Sarras Jr.*, Alexey. A. Leontovich*, Ansgar. S. Olsen, and Robert. V. Intine. (*Co-first authors) Impaired tissue regeneration corresponds with altered expression of developmental genes that persists in the metabolic memory state of diabetic zebrafish. J. Wound Healing and Tissue Regeneration. 2013, 21(2), 320-328.

Pisano*, G., Mason*, S.M., Dhliway, N., Intine, R.V., Sarras, M.P. Jr. (*Co-first authors) An Assay for Lateral Line Regeneration in Adult Zebrafish. JOVE, 2014, Apr 8;(86). doi: 10.3791/51343.

Dhliwayo, Nyembezi, Sarras Michael Jr., Mason, Samantha, and Intine, Robert. Parp inhibition prevents ten eleven translocase enzyme activation and hyperglycemia induced DNA demethylation. Diabetes, 2014, 63:3069–3076. doi: 10.2337/db13-1916.

Michael P. Sarras Jr., Samantha Mason, Geoffrey McAllister, and Robert V. Intine. Inhibition of Poly-ADP Ribose Polymerase Enzyme Activity Prevents Hyperglycemia-Induced Impairment of Angiogenesis during Wound Healing. 2014, Sep;22(5):666-70.

B. Invited Reviews:

Robert V. Intine and Michael P. Sarras Jr. Metabolic Memory and Chronic Diabetes Complications: Potential Role for Epigenetic Mechanisms. Curr. Diab. Rep. 12 (5):551-9, 2012.

C. Invited Book Chapters:

Michael P. Sarras Jr. and Robert V Intine. Use of Zebrafish as a Disease Model Provides a Unique Window For Understanding the Molecular Basis of Diabetic Metabolic Memory. iConcept Press, 2013.



Life in Discovery
Important Links