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Grace E. Stutzmann (Beth), Ph.D.

Associate Professor
Department of Neuroscience
Chicago Medical School
Room 2.216
Building: BSB
Phone: 847.578.8540
Fax: 847.578.8515

Peer Reviewed

Minabe Y, Emori K, Toor A, Stutzmann GE, Ashby CR (1996) The effect of the acute and  chronic administration of CP 96,345, a selective neurokinin1 receptor antagonist, on midbrain dopamine neurons in the rat: a single unit, extracellular recording study. Synapse, 22(1):35-45.


Li XF, Stutzmann GE, LeDoux JE (1996) Convergent but temporally separated inputs to lateral amygdala neurons from the auditory thalamus and auditory cortex use different postsynaptic receptors: in vivo intracellular and extracellular recordings in fear conditioning pathways. Learning and Memory, 3(2-3):229-42.


Stutzmann GE, McEwen BS, LeDoux JE (1998) Serotonin modulation of sensory inputs to the lateral amygdala: dependency on corticosterone. Journal of Neuroscience, 18(22):9529-38. 


Stutzmann GE, LeDoux JE (1999) GABAergic antagonists block the inhibitory effects of serotonin in the lateral amygdala: a mechanism for modulation of sensory inputs related to fear conditioning. Journal of Neuroscience, 1(19):1-4. 


Stutzmann GE, Marek GJ, Aghajanian GK (2001) Adenosine preferentially suppresses serotonin2A-receptor enhanced EPSC’s in layer V neurons of the medial prefrontal cortex. Neuroscience, 105:55-69.


Marchant J, Stutzmann GE, Leissring M, LaFerla F, Parker I (2001) Multiphoton-evoked color change of DsRed as an optical highlighter for cellular and subcellular labeling. Nature Biotechnology, 19:645-649.


Stutzmann GE, LaFerla FM, Parker I (2003) Ca2+ signaling in mouse cortical neurons studied by two-photon imaging and photoreleased inositol triphosphate. Journal of Neuroscience, 23(3):758-65.


Stutzmann GE, Caccamo A, LaFerla FM, Parker I (2004) Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.  Journal of Neuroscience, 24(2) 508-513. 


Stutzmann GE, Smith I, Caccamo A, Oddo S, LaFerla FM, Parker I (2006) Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult and aged Alzheimer’s disease mice. Journal of Neuroscience, 26(20) 5180-5189. 


Stutzmann GE, Smith I, Caccamo A, Oddo S, Parker I, LaFerla F (2007) Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer mouse models.  Annals of the New York Academy of Science, 1097: 265-277.


Chakroborty S, Goussakov I, Miller MB, Stutzmann, GE (2009) Deviant ryanodine receptor-mediated calcium release resets synaptic homeostasis in presymptomatic 3xTg-AD mice. Journal of Neuroscience, 29: 9458-9470. *Faculty of 1000 Recommended Reading Award


Goussakov I, Miller M, Stutzmann GE (2010) NMDA-mediated Ca2+ influx drives ryanodine receptor activation in dendrites of young Alzheimer's disease mice. Journal of Neuroscience, 30(36):12128-37.


Perez MF, Ford K, Goussakov I, Stutzmann, GE, Hu XT (2011) Chronic exposure to cocaine disturbs dopamine D2 receptor modulation of Ca2+ homeostasis in rat nucleus accumbens neurons. Synapse, 65(2):168-80.


Goussakov I, Chakroborty S, Stutzmann GE (2011) Generation of dendritic Ca2+ oscillations as a consequence of altered ryanodine receptor function in AD neurons.  Channels, 5(1):9-13.


Bruno A, Huang J, Bennett DA, Marr R, Hastings ML, Stutzmann GE (2011) Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer’s Disease. Neurobiology of Aging 33(5):1001.e1-6. 


        Chakroborty S, Kim J, Schneider C, Jacobson C, Molgó J, Stutzmann GE. (2012a) Early pre- and postsynaptic calcium signaling abnormalities mask underlying synaptic depression in presymptomatic Alzheimer's disease mice Journal of Neuroscience, 32(24):8341-53. 


Ferrario CR, Goussakov I, Stutzmann GE, Wolf ME. (2012) Withdrawal from cocaine self-administration alters NMDA receptor-mediated Ca2+ entry in nucleus accumbens dendritic spines. PLOS One, 7(8): e40898.


        Chakroborty S, Briggs C, Miller MB, Goussakov I, Schneider C, Kim J, Wicks J, Richardson J, Conklin V, Cameransi B, Stutzmann GE (2012b) Stabilizing ER calcium channel function as an early prevention strategy for Alzheimer’s disease. PLoS One, 7(12): e52056.


        Briggs CA, Schneider C, Richardson JC, Stutzmann GE (2013) Beta amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice. Neurobiology of Aging, 34(6):1632-43.


        Invited Reviews

Stutzmann GE, Parker I (2005) Dynamic multi-photon imaging: a live view from cells to systems.  Physiology, 20:15-21.


Stutzmann GE (2005) Calcium dysregulation, IP3, and Alzheimer’s disease. The Neuroscientist, 11(2):110-5.


Stutzmann GE (2007) The pathogenesis of Alzheimer disease: Is it a lifelong ‘calciumopathy’?  The Neuroscientist, 13(5):546-59. 


Stutzmann GE (2008) Seeing the brain in action: how multiphoton imaging has advanced our understanding of neuronal function.  Microscopy and Microanalysis, 14(6):482-91. *Best Biological Paper Award.


Demuro A, Parker I, Stutzmann GE (2010) Calcium signaling and amyloid toxicity in   Alzheimer's disease. Journal of Biological Chemistry, 285(17):12463-8.


Stutzmann GE, Mattson MP (2011) Endoplasmic reticulum Ca2+ handling in excitable cells in health and disease. Pharmacological Reviews, 63(3):700-27.


Chakroborty S, Stutzmann GE (2011) Early calcium dysregulation in Alzheimer's disease: setting the stage for synaptic dysfunction. Life Science, 54(8):752-762.


Chakroborty S, Stutzmann GE (2013) Calcium Channelopathies and Alzheimer’s Disease: Insight into Therapeutic Success and Failures.  European Journal of Pharmacology.


Life in Discovery
Neuroscience Faculty